Progress in the treatment of advanced gastric cancer
Gastric cancer is one of the most common malignant tumors in the digestive system. Surgery is currently considered to be the only radical treatment. As surgical techniques improve and progress is made in traditional radiotherapy, chemotherapy, and the implementation of neoadjuvant therapy, the 5-yea...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2017-06-01
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| Series: | Tumor Biology |
| Online Access: | https://doi.org/10.1177/1010428317714626 |
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| _version_ | 1849396525604536320 |
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| author | Zheyu Song Yuanyu Wu Jiebing Yang Dingquan Yang Xuedong Fang |
| author_facet | Zheyu Song Yuanyu Wu Jiebing Yang Dingquan Yang Xuedong Fang |
| author_sort | Zheyu Song |
| collection | DOAJ |
| description | Gastric cancer is one of the most common malignant tumors in the digestive system. Surgery is currently considered to be the only radical treatment. As surgical techniques improve and progress is made in traditional radiotherapy, chemotherapy, and the implementation of neoadjuvant therapy, the 5-year survival rate of early gastric cancer can reach >95%. However, the low rate of early diagnosis means that most patients have advanced-stage disease at diagnosis and so the best surgical window is missed. Therefore, the main treatment for advanced gastric cancer is the combination of neoadjuvant chemoradiotherapy, molecular-targeted therapy, and immunotherapy. In this article, we summarize several common methods used to treat advanced gastric cancer and discuss the progress made in the treatment of gastric cancer in detail. Only clinical practice and clinical research will allow us to prolong the survival time of patients and allow the patients to truly benefit by paying attention to the individual patient characteristics, drug choice, and developing a reasonable and comprehensive treatment plan. |
| format | Article |
| id | doaj-art-e90c9bf813df4ff0909617e0e897cbd6 |
| institution | Kabale University |
| issn | 1423-0380 |
| language | English |
| publishDate | 2017-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Tumor Biology |
| spelling | doaj-art-e90c9bf813df4ff0909617e0e897cbd62025-08-20T03:39:18ZengSAGE PublishingTumor Biology1423-03802017-06-013910.1177/1010428317714626Progress in the treatment of advanced gastric cancerZheyu Song0Yuanyu Wu1Jiebing Yang2Dingquan Yang3Xuedong Fang4Department of General Surgery, China–Japan Union Hospital of Jilin University, Changchun, People’s Republic of ChinaDepartment of General Surgery, China–Japan Union Hospital of Jilin University, Changchun, People’s Republic of ChinaKey Laboratory for Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, Changchun, People’s Republic of ChinaDepartment of General Surgery, China–Japan Union Hospital of Jilin University, Changchun, People’s Republic of ChinaDepartment of General Surgery, China–Japan Union Hospital of Jilin University, Changchun, People’s Republic of ChinaGastric cancer is one of the most common malignant tumors in the digestive system. Surgery is currently considered to be the only radical treatment. As surgical techniques improve and progress is made in traditional radiotherapy, chemotherapy, and the implementation of neoadjuvant therapy, the 5-year survival rate of early gastric cancer can reach >95%. However, the low rate of early diagnosis means that most patients have advanced-stage disease at diagnosis and so the best surgical window is missed. Therefore, the main treatment for advanced gastric cancer is the combination of neoadjuvant chemoradiotherapy, molecular-targeted therapy, and immunotherapy. In this article, we summarize several common methods used to treat advanced gastric cancer and discuss the progress made in the treatment of gastric cancer in detail. Only clinical practice and clinical research will allow us to prolong the survival time of patients and allow the patients to truly benefit by paying attention to the individual patient characteristics, drug choice, and developing a reasonable and comprehensive treatment plan.https://doi.org/10.1177/1010428317714626 |
| spellingShingle | Zheyu Song Yuanyu Wu Jiebing Yang Dingquan Yang Xuedong Fang Progress in the treatment of advanced gastric cancer Tumor Biology |
| title | Progress in the treatment of advanced gastric cancer |
| title_full | Progress in the treatment of advanced gastric cancer |
| title_fullStr | Progress in the treatment of advanced gastric cancer |
| title_full_unstemmed | Progress in the treatment of advanced gastric cancer |
| title_short | Progress in the treatment of advanced gastric cancer |
| title_sort | progress in the treatment of advanced gastric cancer |
| url | https://doi.org/10.1177/1010428317714626 |
| work_keys_str_mv | AT zheyusong progressinthetreatmentofadvancedgastriccancer AT yuanyuwu progressinthetreatmentofadvancedgastriccancer AT jiebingyang progressinthetreatmentofadvancedgastriccancer AT dingquanyang progressinthetreatmentofadvancedgastriccancer AT xuedongfang progressinthetreatmentofadvancedgastriccancer |