Lactylation-regulated biomolecular condensates: metabolic control of phase separation in physiology and disease

Abstract Lactate has long been viewed as a “waste product” of anaerobic glycolysis, with its role in health and disease often overlooked. However, recent discoveries of lactylation—a novel post-translational modification involving lactate—have sparked a renewed understanding of lactate’s functions....

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Bibliographic Details
Main Authors: Xi Wang, Jiameng Liu, Chaoming Mao, Yufei Mao
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-025-02244-6
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