Hemophagocytic syndrome triggered by intense physical activity and viral infection in a young adult female with three heterozygous mutations in Munc-18-2

Hemophagocytic syndrome triggered by intense physical activity and viral infection in a young adult female with three heterozygous mutations in Munc-18-2

Introduction. Hemophagocytic lymphohistiocytosis (HLH) is a rare, potentially life-threatening, hyperinflammatory syndrome caused by severe hypercytokinemia due to a highly stimulated, but ineffective immune response. Case report. We reported a 19-year-old woman presenting with fever, muscle and joi...

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Bibliographic Details
Main Authors: Marković Olivera, Janić Dragana, Pavlović Milorad, Tukić Ljiljana, Janković Srđa, Filipović Branka, Marisavljević Dragomir
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2017-01-01
Series:Vojnosanitetski Pregled
Subjects:
lymphohistocytosis, hemophagocytic
inflammation
immunologic factors
physical exertion
ebstein-barr virus
mutation
diagnosis, differential
drug therapy
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600224M.pdf
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