Baclofen-induced pancreatitis
Acute pancreatitis is an inflammatory condition of the pancreas that can result from various aetiologies, one of them being drug-induced pancreatitis, a relatively rare cause. Drug-induced pancreatitis should be considered in patients presenting with epigastric pain, elevated pancreatic enzymes, and...
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| Format: | Article |
| Language: | English |
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SMC MEDIA SRL
2025-04-01
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| Series: | European Journal of Case Reports in Internal Medicine |
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| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/5393 |
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| _version_ | 1850203176567832576 |
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| author | Nicolas Nassif Nadia Katrib Karam Karam Elias Fiani |
| author_facet | Nicolas Nassif Nadia Katrib Karam Karam Elias Fiani |
| author_sort | Nicolas Nassif |
| collection | DOAJ |
| description | Acute pancreatitis is an inflammatory condition of the pancreas that can result from various aetiologies, one of them being drug-induced pancreatitis, a relatively rare cause. Drug-induced pancreatitis should be considered in patients presenting with epigastric pain, elevated pancreatic enzymes, and imaging findings consistent with acute pancreatitis, in the absence of any common precipitants such as alcohol, gallstones, trauma. We report a case of acute pancreatitis following the initiation of baclofen therapy, with no other identifiable risk factors. A probable drug adverse reaction was established through the Naranjo Adverse Drug Reaction Probability Scale. This case highlights the need for physicians to consider baclofen as a potential cause of acute pancreatitis. |
| format | Article |
| id | doaj-art-e8fcb1b4aaef4340bb08fdada59abb20 |
| institution | OA Journals |
| issn | 2284-2594 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj-art-e8fcb1b4aaef4340bb08fdada59abb202025-08-20T02:11:34ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942025-04-0110.12890/2025_0053934928Baclofen-induced pancreatitisNicolas Nassif0Nadia Katrib1Karam Karam2Elias Fiani3Department of Internal Medicine, University of Balamand, Beirut, LebanonDepartment of Internal Medicine, University of Balamand, Beirut, LebanonDepartment of Gastroenterology and Hepatology, University of Balamand, Beirut, LebanonDepartment of Gastroenterology and Hepatology, University of Balamand, Beirut, LebanonAcute pancreatitis is an inflammatory condition of the pancreas that can result from various aetiologies, one of them being drug-induced pancreatitis, a relatively rare cause. Drug-induced pancreatitis should be considered in patients presenting with epigastric pain, elevated pancreatic enzymes, and imaging findings consistent with acute pancreatitis, in the absence of any common precipitants such as alcohol, gallstones, trauma. We report a case of acute pancreatitis following the initiation of baclofen therapy, with no other identifiable risk factors. A probable drug adverse reaction was established through the Naranjo Adverse Drug Reaction Probability Scale. This case highlights the need for physicians to consider baclofen as a potential cause of acute pancreatitis.https://www.ejcrim.com/index.php/EJCRIM/article/view/5393acute pancreatitisbaclofendrug-induced pancreatitisnaranjo score |
| spellingShingle | Nicolas Nassif Nadia Katrib Karam Karam Elias Fiani Baclofen-induced pancreatitis European Journal of Case Reports in Internal Medicine acute pancreatitis baclofen drug-induced pancreatitis naranjo score |
| title | Baclofen-induced pancreatitis |
| title_full | Baclofen-induced pancreatitis |
| title_fullStr | Baclofen-induced pancreatitis |
| title_full_unstemmed | Baclofen-induced pancreatitis |
| title_short | Baclofen-induced pancreatitis |
| title_sort | baclofen induced pancreatitis |
| topic | acute pancreatitis baclofen drug-induced pancreatitis naranjo score |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/5393 |
| work_keys_str_mv | AT nicolasnassif baclofeninducedpancreatitis AT nadiakatrib baclofeninducedpancreatitis AT karamkaram baclofeninducedpancreatitis AT eliasfiani baclofeninducedpancreatitis |