Pathological features of the structure of the female genital organs from fetuses of mothers with complicated pregnancies

Aim. In the course of the study the structural features of fetal ovarian of mothers with severe preeclampsia in comparison with fetuses from healthy mothers were revealed. Methods and results. Proliferation of connective tissue; mass mortality of the ovocytes; the prevalence of perishing primordi...

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Main Author: L. S. Kupriyanova
Format: Article
Language:English
Published: Zaporizhzhia State Medical and Pharmaceutical University 2015-08-01
Series:Zaporožskij Medicinskij Žurnal
Subjects:
Online Access:http://zmj.zsmu.edu.ua/article/view/50301/47705
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author L. S. Kupriyanova
author_facet L. S. Kupriyanova
author_sort L. S. Kupriyanova
collection DOAJ
description Aim. In the course of the study the structural features of fetal ovarian of mothers with severe preeclampsia in comparison with fetuses from healthy mothers were revealed. Methods and results. Proliferation of connective tissue; mass mortality of the ovocytes; the prevalence of perishing primordial follicles in the follicular unit were demonstrated histologically. Histochemical methods established reduction in the intensity of the reaction to DNP in the nucleus and in the RNP in the cells cytoplasm. Morphometric method showed significant reduction in the relative volume of the follicular tissue, as well as a significant increase in the relative volume of the interstitial tissue. The described type of fetal ovarian structure of mothers with severe PE corresponds to hypoplastic type and constitutes a violation of the gonads formation in utero. Conclusion. The revealed features of the fetal ovaries structure can contribute to a violation of the germinal function in the further ontogenesis
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issn 2306-4145
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language English
publishDate 2015-08-01
publisher Zaporizhzhia State Medical and Pharmaceutical University
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series Zaporožskij Medicinskij Žurnal
spelling doaj-art-e8f6b55b3abb44bd9a5b389fbdeac1632025-08-20T03:21:08ZengZaporizhzhia State Medical and Pharmaceutical UniversityZaporožskij Medicinskij Žurnal2306-41452310-12102015-08-0146871http://dx.doi.org/10.14739/2310-1210.2015.4.50301Pathological features of the structure of the female genital organs from fetuses of mothers with complicated pregnanciesL. S. KupriyanovaAim. In the course of the study the structural features of fetal ovarian of mothers with severe preeclampsia in comparison with fetuses from healthy mothers were revealed. Methods and results. Proliferation of connective tissue; mass mortality of the ovocytes; the prevalence of perishing primordial follicles in the follicular unit were demonstrated histologically. Histochemical methods established reduction in the intensity of the reaction to DNP in the nucleus and in the RNP in the cells cytoplasm. Morphometric method showed significant reduction in the relative volume of the follicular tissue, as well as a significant increase in the relative volume of the interstitial tissue. The described type of fetal ovarian structure of mothers with severe PE corresponds to hypoplastic type and constitutes a violation of the gonads formation in utero. Conclusion. The revealed features of the fetal ovaries structure can contribute to a violation of the germinal function in the further ontogenesishttp://zmj.zsmu.edu.ua/article/view/50301/47705FetusOvaryPregnancy ComplicationsPre-Eclampsiya
spellingShingle L. S. Kupriyanova
Pathological features of the structure of the female genital organs from fetuses of mothers with complicated pregnancies
Zaporožskij Medicinskij Žurnal
Fetus
Ovary
Pregnancy Complications
Pre-Eclampsiya
title Pathological features of the structure of the female genital organs from fetuses of mothers with complicated pregnancies
title_full Pathological features of the structure of the female genital organs from fetuses of mothers with complicated pregnancies
title_fullStr Pathological features of the structure of the female genital organs from fetuses of mothers with complicated pregnancies
title_full_unstemmed Pathological features of the structure of the female genital organs from fetuses of mothers with complicated pregnancies
title_short Pathological features of the structure of the female genital organs from fetuses of mothers with complicated pregnancies
title_sort pathological features of the structure of the female genital organs from fetuses of mothers with complicated pregnancies
topic Fetus
Ovary
Pregnancy Complications
Pre-Eclampsiya
url http://zmj.zsmu.edu.ua/article/view/50301/47705
work_keys_str_mv AT lskupriyanova pathologicalfeaturesofthestructureofthefemalegenitalorgansfromfetusesofmotherswithcomplicatedpregnancies