A Mathematical Model for Effective Control and Possible Eradication of Malaria

In this paper, a deterministic mathematical model for the transmission and control of malaria is formulated. The main innovation in the model is that, in addition to the natural death rate of the vector (mosquito), a proportion of the prevention efforts also contributes to a reduction of the mosquit...

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Main Authors: Agnes Adom-Konadu, Ernest Yankson, Samuel M. Naandam, Duah Dwomoh
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Mathematics
Online Access:http://dx.doi.org/10.1155/2022/6165581
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author Agnes Adom-Konadu
Ernest Yankson
Samuel M. Naandam
Duah Dwomoh
author_facet Agnes Adom-Konadu
Ernest Yankson
Samuel M. Naandam
Duah Dwomoh
author_sort Agnes Adom-Konadu
collection DOAJ
description In this paper, a deterministic mathematical model for the transmission and control of malaria is formulated. The main innovation in the model is that, in addition to the natural death rate of the vector (mosquito), a proportion of the prevention efforts also contributes to a reduction of the mosquito population. The motivation for the model is that in a closed environment, an optimal combination of the percentage of susceptible people needed to implement the preventative strategies α and the percentage of infected people needed to seek treatment can reduce both the number of infected humans and infected mosquito populations and eventually eliminate the disease from the community. Prevention effort α was found to be the most sensitive parameter in the reduction of ℛ0. Hence, numerical simulations were performed using different values of α to determine an optimal value of α that reduces the incidence rate fastest. It was discovered that an optimal combination that reduces the incidence rate fastest comes from about 40% of adherence to the preventive strategies coupled with about 40% of infected humans seeking clinical treatment, as this will reduce the infected human and vector populations considerably.
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spelling doaj-art-e8ec73aa5a08481faa70f72126d6d35d2025-08-20T03:21:09ZengWileyJournal of Mathematics2314-47852022-01-01202210.1155/2022/6165581A Mathematical Model for Effective Control and Possible Eradication of MalariaAgnes Adom-Konadu0Ernest Yankson1Samuel M. Naandam2Duah Dwomoh3Department of MathematicsDepartment of MathematicsDepartment of MathematicsDepartment of BiostatisticsIn this paper, a deterministic mathematical model for the transmission and control of malaria is formulated. The main innovation in the model is that, in addition to the natural death rate of the vector (mosquito), a proportion of the prevention efforts also contributes to a reduction of the mosquito population. The motivation for the model is that in a closed environment, an optimal combination of the percentage of susceptible people needed to implement the preventative strategies α and the percentage of infected people needed to seek treatment can reduce both the number of infected humans and infected mosquito populations and eventually eliminate the disease from the community. Prevention effort α was found to be the most sensitive parameter in the reduction of ℛ0. Hence, numerical simulations were performed using different values of α to determine an optimal value of α that reduces the incidence rate fastest. It was discovered that an optimal combination that reduces the incidence rate fastest comes from about 40% of adherence to the preventive strategies coupled with about 40% of infected humans seeking clinical treatment, as this will reduce the infected human and vector populations considerably.http://dx.doi.org/10.1155/2022/6165581
spellingShingle Agnes Adom-Konadu
Ernest Yankson
Samuel M. Naandam
Duah Dwomoh
A Mathematical Model for Effective Control and Possible Eradication of Malaria
Journal of Mathematics
title A Mathematical Model for Effective Control and Possible Eradication of Malaria
title_full A Mathematical Model for Effective Control and Possible Eradication of Malaria
title_fullStr A Mathematical Model for Effective Control and Possible Eradication of Malaria
title_full_unstemmed A Mathematical Model for Effective Control and Possible Eradication of Malaria
title_short A Mathematical Model for Effective Control and Possible Eradication of Malaria
title_sort mathematical model for effective control and possible eradication of malaria
url http://dx.doi.org/10.1155/2022/6165581
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