Optimization of Carbon and Nitrogen Source on the Production of Pectinase Enzymes in Solid-state Fermentation by Cyberlindnera fabianii UNJCC Y-144 and Candida tropicalis UNJCC Y-148-149 Isolated from Lai Fruit

Yeasts are prevalent on the surfaces and within the pulp of ripening fruits, where they utilize available sugars and nutrients to thrive. This study focuses on the endemic Lai fruit (Durio sp.) from Kalimantan, Indonesia, which contains pectin, a key substrate for pectinolytic yeasts. The activity o...

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Main Authors: Dalia Sukmawati, Adisyahputra, Rifdah Hasanah, Shabrina Nida Al Husna, Nuniek Ina Ratnaningtyas, Adil Aksoy, Hesham Ali El-Enshasy
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Language:English
Published: Journal of Pure and Applied Microbiology 2025-06-01
Series:Journal of Pure and Applied Microbiology
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Online Access:https://microbiologyjournal.org/optimization-of-carbon-and-nitrogen-source-on-the-production-of-pectinase-enzymes-in-solid-state-fermentation-by-cyberlindnera-fabianii-unjcc-y-144-and-candida-tropicalis-unjcc-y-148-149-isolated-from/
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author Dalia Sukmawati
Adisyahputra
Rifdah Hasanah
Shabrina Nida Al Husna
Nuniek Ina Ratnaningtyas
Adil Aksoy
Hesham Ali El-Enshasy
author_facet Dalia Sukmawati
Adisyahputra
Rifdah Hasanah
Shabrina Nida Al Husna
Nuniek Ina Ratnaningtyas
Adil Aksoy
Hesham Ali El-Enshasy
author_sort Dalia Sukmawati
collection DOAJ
description Yeasts are prevalent on the surfaces and within the pulp of ripening fruits, where they utilize available sugars and nutrients to thrive. This study focuses on the endemic Lai fruit (Durio sp.) from Kalimantan, Indonesia, which contains pectin, a key substrate for pectinolytic yeasts. The activity of these yeasts, particularly in producing pectinase enzymes, is influenced by the carbon and nitrogen resources present in the fruit. We aimed to evaluate the effects of varying carbon sources (glucose, sucrose, and pectin) and nitrogen sources (peptone, urea, and ammonium chloride) on the pectinase activity of yeasts isolated from Lai fruit. In our screening, five out of twenty yeast isolates demonstrated pectinase production, with three isolates UNJCC Y-144, UNJCC Y-148, and UNJCC Y-149 selected for further analysis. The initial screening revealed pectinolytic index values of 0.55 ± 0.07 mm, 0.45 ± 0.02 mm, and 0.49 ± 0.06 mm for UNJCC Y-144, UNJCC Y-148, and UNJCC Y-149, respectively. Molecular identification confirmed that UNJCC Y-144 is Cyberlindnera fabianii (100% homology), while UNJCC Y-148 and UNJCC Y-149 are Candida tropicalis (100% and 99.83% homology, respectively). Notably, Cyberlindnera fabianii UNJCC Y-144 exhibited the enzyme activity (EA) in a medium lacking pectin, ranging from 48.68 ± 2.84 to 32.05 ± 2.46 U/mL. These findings underscore the potential of utilizing local yeasts for biotechnological applications in enzyme production, particularly in the food industry, where pectinase plays a critical role in processing fruit and improving juice extraction efficiency.
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spelling doaj-art-e8eac1126b4442c7956129ba2adaa68e2025-08-20T03:21:22ZengJournal of Pure and Applied MicrobiologyJournal of Pure and Applied Microbiology0973-75102581-690X2025-06-0119210101026https://doi.org/10.22207/JPAM.19.2.04Optimization of Carbon and Nitrogen Source on the Production of Pectinase Enzymes in Solid-state Fermentation by Cyberlindnera fabianii UNJCC Y-144 and Candida tropicalis UNJCC Y-148-149 Isolated from Lai FruitDalia Sukmawatihttps://orcid.org/0000-0001-9641-9321Adisyahputrahttps://orcid.org/0000-0001-8182-3508Rifdah Hasanahhttps://orcid.org/0000-0002-5534-8536Shabrina Nida Al Husnahttps://orcid.org/0000-0002-2635-198XNuniek Ina Ratnaningtyashttps://orcid.org/0000-0002-7841-1999Adil Aksoyhttps://orcid.org/0000-0002-1521-3100Hesham Ali El-Enshasyhttps://orcid.org/0000-0002-9712-2033Yeasts are prevalent on the surfaces and within the pulp of ripening fruits, where they utilize available sugars and nutrients to thrive. This study focuses on the endemic Lai fruit (Durio sp.) from Kalimantan, Indonesia, which contains pectin, a key substrate for pectinolytic yeasts. The activity of these yeasts, particularly in producing pectinase enzymes, is influenced by the carbon and nitrogen resources present in the fruit. We aimed to evaluate the effects of varying carbon sources (glucose, sucrose, and pectin) and nitrogen sources (peptone, urea, and ammonium chloride) on the pectinase activity of yeasts isolated from Lai fruit. In our screening, five out of twenty yeast isolates demonstrated pectinase production, with three isolates UNJCC Y-144, UNJCC Y-148, and UNJCC Y-149 selected for further analysis. The initial screening revealed pectinolytic index values of 0.55 ± 0.07 mm, 0.45 ± 0.02 mm, and 0.49 ± 0.06 mm for UNJCC Y-144, UNJCC Y-148, and UNJCC Y-149, respectively. Molecular identification confirmed that UNJCC Y-144 is Cyberlindnera fabianii (100% homology), while UNJCC Y-148 and UNJCC Y-149 are Candida tropicalis (100% and 99.83% homology, respectively). Notably, Cyberlindnera fabianii UNJCC Y-144 exhibited the enzyme activity (EA) in a medium lacking pectin, ranging from 48.68 ± 2.84 to 32.05 ± 2.46 U/mL. These findings underscore the potential of utilizing local yeasts for biotechnological applications in enzyme production, particularly in the food industry, where pectinase plays a critical role in processing fruit and improving juice extraction efficiency.https://microbiologyjournal.org/optimization-of-carbon-and-nitrogen-source-on-the-production-of-pectinase-enzymes-in-solid-state-fermentation-by-cyberlindnera-fabianii-unjcc-y-144-and-candida-tropicalis-unjcc-y-148-149-isolated-from/carbon and nitrogen sourcespectinase productionsolid-state fermentationcyberlindnera fabianiicandida tropicalislai fruit
spellingShingle Dalia Sukmawati
Adisyahputra
Rifdah Hasanah
Shabrina Nida Al Husna
Nuniek Ina Ratnaningtyas
Adil Aksoy
Hesham Ali El-Enshasy
Optimization of Carbon and Nitrogen Source on the Production of Pectinase Enzymes in Solid-state Fermentation by Cyberlindnera fabianii UNJCC Y-144 and Candida tropicalis UNJCC Y-148-149 Isolated from Lai Fruit
Journal of Pure and Applied Microbiology
carbon and nitrogen sources
pectinase production
solid-state fermentation
cyberlindnera fabianii
candida tropicalis
lai fruit
title Optimization of Carbon and Nitrogen Source on the Production of Pectinase Enzymes in Solid-state Fermentation by Cyberlindnera fabianii UNJCC Y-144 and Candida tropicalis UNJCC Y-148-149 Isolated from Lai Fruit
title_full Optimization of Carbon and Nitrogen Source on the Production of Pectinase Enzymes in Solid-state Fermentation by Cyberlindnera fabianii UNJCC Y-144 and Candida tropicalis UNJCC Y-148-149 Isolated from Lai Fruit
title_fullStr Optimization of Carbon and Nitrogen Source on the Production of Pectinase Enzymes in Solid-state Fermentation by Cyberlindnera fabianii UNJCC Y-144 and Candida tropicalis UNJCC Y-148-149 Isolated from Lai Fruit
title_full_unstemmed Optimization of Carbon and Nitrogen Source on the Production of Pectinase Enzymes in Solid-state Fermentation by Cyberlindnera fabianii UNJCC Y-144 and Candida tropicalis UNJCC Y-148-149 Isolated from Lai Fruit
title_short Optimization of Carbon and Nitrogen Source on the Production of Pectinase Enzymes in Solid-state Fermentation by Cyberlindnera fabianii UNJCC Y-144 and Candida tropicalis UNJCC Y-148-149 Isolated from Lai Fruit
title_sort optimization of carbon and nitrogen source on the production of pectinase enzymes in solid state fermentation by cyberlindnera fabianii unjcc y 144 and candida tropicalis unjcc y 148 149 isolated from lai fruit
topic carbon and nitrogen sources
pectinase production
solid-state fermentation
cyberlindnera fabianii
candida tropicalis
lai fruit
url https://microbiologyjournal.org/optimization-of-carbon-and-nitrogen-source-on-the-production-of-pectinase-enzymes-in-solid-state-fermentation-by-cyberlindnera-fabianii-unjcc-y-144-and-candida-tropicalis-unjcc-y-148-149-isolated-from/
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