Genetic and biochemical characterizations of Zika virus NS2A protein

Genetic and biochemical characterizations of Zika virus NS2A protein

Zika virus (ZIKV) can cause devastating congenital Zika syndromes in pregnant women and Guillain-Barre syndrome in adults. Understanding the molecular mechanism of ZIKV replication is essential for antiviral and vaccine development. Here we report the structural and functional characterization of ZI...

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Bibliographic Details
Main Authors: Xianwen Zhang, Xuping Xie, Jing Zou, Hongjie Xia, Chao Shan, Xinwen Chen, Pei-Yong Shi
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
Subjects:
Zika virus
flavivirus replication
virion assembly
flavivirus NS2A
membrane topology
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2019.1598291
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