Primary intestinal lymphangiectasia in adults - diagnostic and therapeutic challenge
Introduction. Primary intestinal lymphangiectasia is a rare disorder, characterized by abnormal dilation of intestinal lymphatic vessels and extensive enteric loss of lymph rich in plasma proteins, lymphocytes and chylomicrons. The main characteristics of the disease are hypoalbuminemia, hypogammagl...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2018-01-01
|
| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600320J.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849472066148892672 |
|---|---|
| author | Jocić Tatiana Latinović-Bošnjak Olgica Živojinov Mirjana Stojšić Mirjana Ilić-Sabo Jelena |
| author_facet | Jocić Tatiana Latinović-Bošnjak Olgica Živojinov Mirjana Stojšić Mirjana Ilić-Sabo Jelena |
| author_sort | Jocić Tatiana |
| collection | DOAJ |
| description | Introduction. Primary intestinal lymphangiectasia is a rare disorder, characterized by abnormal dilation of intestinal lymphatic vessels and extensive enteric loss of lymph rich in plasma proteins, lymphocytes and chylomicrons. The main characteristics of the disease are hypoalbuminemia, hypogammaglobulinemia, lymphocytopenia, and more rarely, the deficit of liposoluble vitamins and anemia. Except for primary, there are secondary lymphangiectasia, associated with celiac disease, malignant, infective and inflammatory diseases of the small intestine, fibrosis, liver and cardiovascular diseases. Case report. A male, 33 years of age, presented for his medical examination suffering from diarrhea and edema. The diagnosis was established upon the histological examination of a small intestine biopsy during double balloon enteroscopy, which revealed changes only in one segment of the intestine examined. Such a finding was later confirmed by the video endoscopy capsule. Conclusion. The diagnosis of intestinal lymphangiectasia is usually established before the age of 3, but it can also be diagnosed in adults. The diagnosis is based on the histological analysis of the intestinal mucosa biopsy, obtained by endoscopic procedures. The diagnosis of primary intestinal lymphangiectasia is also made upon the exclusion of secondary causes. |
| format | Article |
| id | doaj-art-e8e3b050d0a140809695b3df576d83b1 |
| institution | Kabale University |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-e8e3b050d0a140809695b3df576d83b12025-08-20T03:24:38ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202018-01-01751959910.2298/VSP160210320J0042-84501600320JPrimary intestinal lymphangiectasia in adults - diagnostic and therapeutic challengeJocić Tatiana0Latinović-Bošnjak Olgica1Živojinov Mirjana2Stojšić Mirjana3Ilić-Sabo Jelena4Clinical Center of Vojvodina, Clinic of Gastroenterology and Hepatology, Novi SadClinical Center of Vojvodina, Clinic of Gastroenterology and Hepatology, Novi SadClinical Center of Vojvodina, Center for Pathology and Histology, Novi SadClinical Center of Vojvodina, Institute of Child and Youth Health Care, Department of Gastroenterohepatology and Nutrition, Novi Sad Clinical Center of Vojvodina, Center for Pathology and Histology, Novi SadIntroduction. Primary intestinal lymphangiectasia is a rare disorder, characterized by abnormal dilation of intestinal lymphatic vessels and extensive enteric loss of lymph rich in plasma proteins, lymphocytes and chylomicrons. The main characteristics of the disease are hypoalbuminemia, hypogammaglobulinemia, lymphocytopenia, and more rarely, the deficit of liposoluble vitamins and anemia. Except for primary, there are secondary lymphangiectasia, associated with celiac disease, malignant, infective and inflammatory diseases of the small intestine, fibrosis, liver and cardiovascular diseases. Case report. A male, 33 years of age, presented for his medical examination suffering from diarrhea and edema. The diagnosis was established upon the histological examination of a small intestine biopsy during double balloon enteroscopy, which revealed changes only in one segment of the intestine examined. Such a finding was later confirmed by the video endoscopy capsule. Conclusion. The diagnosis of intestinal lymphangiectasia is usually established before the age of 3, but it can also be diagnosed in adults. The diagnosis is based on the histological analysis of the intestinal mucosa biopsy, obtained by endoscopic procedures. The diagnosis of primary intestinal lymphangiectasia is also made upon the exclusion of secondary causes.http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600320J.pdfdiarrhealympangiectasishypoalbuminemialymphopeniaprotein-losing enteropathies |
| spellingShingle | Jocić Tatiana Latinović-Bošnjak Olgica Živojinov Mirjana Stojšić Mirjana Ilić-Sabo Jelena Primary intestinal lymphangiectasia in adults - diagnostic and therapeutic challenge Vojnosanitetski Pregled diarrhea lympangiectasis hypoalbuminemia lymphopenia protein-losing enteropathies |
| title | Primary intestinal lymphangiectasia in adults - diagnostic and therapeutic challenge |
| title_full | Primary intestinal lymphangiectasia in adults - diagnostic and therapeutic challenge |
| title_fullStr | Primary intestinal lymphangiectasia in adults - diagnostic and therapeutic challenge |
| title_full_unstemmed | Primary intestinal lymphangiectasia in adults - diagnostic and therapeutic challenge |
| title_short | Primary intestinal lymphangiectasia in adults - diagnostic and therapeutic challenge |
| title_sort | primary intestinal lymphangiectasia in adults diagnostic and therapeutic challenge |
| topic | diarrhea lympangiectasis hypoalbuminemia lymphopenia protein-losing enteropathies |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2018/0042-84501600320J.pdf |
| work_keys_str_mv | AT jocictatiana primaryintestinallymphangiectasiainadultsdiagnosticandtherapeuticchallenge AT latinovicbosnjakolgica primaryintestinallymphangiectasiainadultsdiagnosticandtherapeuticchallenge AT zivojinovmirjana primaryintestinallymphangiectasiainadultsdiagnosticandtherapeuticchallenge AT stojsicmirjana primaryintestinallymphangiectasiainadultsdiagnosticandtherapeuticchallenge AT ilicsabojelena primaryintestinallymphangiectasiainadultsdiagnosticandtherapeuticchallenge |