Assessment of Accuracy in Calculating Hemodynamic Parameters and Left Ventricular Mass According to ECG-Synchronized Myocardial Perfusion Scintigraphic Data: Comparison with Cardiac Multislice Computed Tomography
Objective. To assess accuracy in calculating the values of end-diastolic and end-systolic volumes (EDV and ESV), ejection fraction (EF), and left ventricular (LV) mass, which are obtained according to ECG-synchronized myocardial perfusion scintigraphy (ECG-MPS) on a CZT camera versus those of cardi...
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Luchevaya Diagnostika, LLC
2019-06-01
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| Series: | Вестник рентгенологии и радиологии |
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| Online Access: | https://www.russianradiology.ru/jour/article/view/469 |
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| author | V. V. Saushkin K. V. Zavadovskiy |
| author_facet | V. V. Saushkin K. V. Zavadovskiy |
| author_sort | V. V. Saushkin |
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| description | Objective. To assess accuracy in calculating the values of end-diastolic and end-systolic volumes (EDV and ESV), ejection fraction (EF), and left ventricular (LV) mass, which are obtained according to ECG-synchronized myocardial perfusion scintigraphy (ECG-MPS) on a CZT camera versus those of cardiac multislice computed tomography (MSCT).Material and methods. Thirty-four patients (mean age, 62 ± 5 years) with suspected coronary heart disease or its previously established diagnosis were examined. All the patients underwent MSCT coronary angiography and myocardial perfusion scintigraphy with 99mTc-methyxy-isobutyl-isonitrile. For a comparative analysis, the investigators used the EDV, ESV, FV and LV mass values determined by ECG-MPS at rest and cardiac MSCT. The studies were conducted on a 64-slice SPECT/CT hybrid scanner (Discovery 570c, GE Healthcare, USA).Results. The analysis of the results obtained by both methods revealed statistically significant differences in the values of EDV (MSCT: 168 (145–210) ml; ECG-MPS: 112 (94–141) ml; p < 0.05), ESV (MSCT: 72 (49–83) ml; ECG-MPS: 44 (32–66) ml; p < 0.05), and LV mass (MSCT: 123 (107–143) g; ECG-MPS: 140 (124–168) g; p < 0.05). There were no significant differences in LV EF (MSCT: 64 (54–69)%; ECG-MPS: 61 (50–66)%; p > 0.05). There was a statistically significant correlation between the values of EDV, ESV, and LV mass (r = 0.81; r = 0.78; r = 0.82, respectively, p < 0.05) and a mean correlation of LV EF (r = 0.66; p < 0.05). The Bland–Altman analysis showed that the values of EDV, ESV, and LV mass had statistically significant differences. The consistency limits for the indicators were as follows: EDV, 9–105 ml; ESV, 9–55 ml; LV mass, 51.6–20.7 g. There was a measurement consistency only for EF (consent limits, 16.9–18.4%; p < 0.05). Linear regression equations were calculated, which allow determination of exact values for the volume indices and LV mass according ECG-MPS data.Conclusion. The scintigraphic method versus MSCT yields significantly smaller volumes (EDV and ESV) and higher LV mass. The ECG-MPS values for EDV, ESV, EF, and LV mass have a statistically significant strong correlation with MSCT findings. At the same time, a good consistency of measurements was found only for LV EF. |
| format | Article |
| id | doaj-art-e8e10b5caae14d6f92edb074f28a247d |
| institution | Kabale University |
| issn | 0042-4676 2619-0478 |
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| publishDate | 2019-06-01 |
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| spelling | doaj-art-e8e10b5caae14d6f92edb074f28a247d2025-08-20T03:35:07ZengLuchevaya Diagnostika, LLCВестник рентгенологии и радиологии0042-46762619-04782019-06-01100315216010.20862/0042-4676-2019-100-3-152-160283Assessment of Accuracy in Calculating Hemodynamic Parameters and Left Ventricular Mass According to ECG-Synchronized Myocardial Perfusion Scintigraphic Data: Comparison with Cardiac Multislice Computed TomographyV. V. Saushkin0K. V. Zavadovskiy1Cardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of SciencesCardiology Research Institute, Tomsk National Research Medical Center of the Russian Academy of SciencesObjective. To assess accuracy in calculating the values of end-diastolic and end-systolic volumes (EDV and ESV), ejection fraction (EF), and left ventricular (LV) mass, which are obtained according to ECG-synchronized myocardial perfusion scintigraphy (ECG-MPS) on a CZT camera versus those of cardiac multislice computed tomography (MSCT).Material and methods. Thirty-four patients (mean age, 62 ± 5 years) with suspected coronary heart disease or its previously established diagnosis were examined. All the patients underwent MSCT coronary angiography and myocardial perfusion scintigraphy with 99mTc-methyxy-isobutyl-isonitrile. For a comparative analysis, the investigators used the EDV, ESV, FV and LV mass values determined by ECG-MPS at rest and cardiac MSCT. The studies were conducted on a 64-slice SPECT/CT hybrid scanner (Discovery 570c, GE Healthcare, USA).Results. The analysis of the results obtained by both methods revealed statistically significant differences in the values of EDV (MSCT: 168 (145–210) ml; ECG-MPS: 112 (94–141) ml; p < 0.05), ESV (MSCT: 72 (49–83) ml; ECG-MPS: 44 (32–66) ml; p < 0.05), and LV mass (MSCT: 123 (107–143) g; ECG-MPS: 140 (124–168) g; p < 0.05). There were no significant differences in LV EF (MSCT: 64 (54–69)%; ECG-MPS: 61 (50–66)%; p > 0.05). There was a statistically significant correlation between the values of EDV, ESV, and LV mass (r = 0.81; r = 0.78; r = 0.82, respectively, p < 0.05) and a mean correlation of LV EF (r = 0.66; p < 0.05). The Bland–Altman analysis showed that the values of EDV, ESV, and LV mass had statistically significant differences. The consistency limits for the indicators were as follows: EDV, 9–105 ml; ESV, 9–55 ml; LV mass, 51.6–20.7 g. There was a measurement consistency only for EF (consent limits, 16.9–18.4%; p < 0.05). Linear regression equations were calculated, which allow determination of exact values for the volume indices and LV mass according ECG-MPS data.Conclusion. The scintigraphic method versus MSCT yields significantly smaller volumes (EDV and ESV) and higher LV mass. The ECG-MPS values for EDV, ESV, EF, and LV mass have a statistically significant strong correlation with MSCT findings. At the same time, a good consistency of measurements was found only for LV EF.https://www.russianradiology.ru/jour/article/view/469myocardial perfusion scintigraphymultislice computed tomographycadmium-zinc-telluriumleft ventricular volume indicesleft ventricular mass |
| spellingShingle | V. V. Saushkin K. V. Zavadovskiy Assessment of Accuracy in Calculating Hemodynamic Parameters and Left Ventricular Mass According to ECG-Synchronized Myocardial Perfusion Scintigraphic Data: Comparison with Cardiac Multislice Computed Tomography Вестник рентгенологии и радиологии myocardial perfusion scintigraphy multislice computed tomography cadmium-zinc-tellurium left ventricular volume indices left ventricular mass |
| title | Assessment of Accuracy in Calculating Hemodynamic Parameters and Left Ventricular Mass According to ECG-Synchronized Myocardial Perfusion Scintigraphic Data: Comparison with Cardiac Multislice Computed Tomography |
| title_full | Assessment of Accuracy in Calculating Hemodynamic Parameters and Left Ventricular Mass According to ECG-Synchronized Myocardial Perfusion Scintigraphic Data: Comparison with Cardiac Multislice Computed Tomography |
| title_fullStr | Assessment of Accuracy in Calculating Hemodynamic Parameters and Left Ventricular Mass According to ECG-Synchronized Myocardial Perfusion Scintigraphic Data: Comparison with Cardiac Multislice Computed Tomography |
| title_full_unstemmed | Assessment of Accuracy in Calculating Hemodynamic Parameters and Left Ventricular Mass According to ECG-Synchronized Myocardial Perfusion Scintigraphic Data: Comparison with Cardiac Multislice Computed Tomography |
| title_short | Assessment of Accuracy in Calculating Hemodynamic Parameters and Left Ventricular Mass According to ECG-Synchronized Myocardial Perfusion Scintigraphic Data: Comparison with Cardiac Multislice Computed Tomography |
| title_sort | assessment of accuracy in calculating hemodynamic parameters and left ventricular mass according to ecg synchronized myocardial perfusion scintigraphic data comparison with cardiac multislice computed tomography |
| topic | myocardial perfusion scintigraphy multislice computed tomography cadmium-zinc-tellurium left ventricular volume indices left ventricular mass |
| url | https://www.russianradiology.ru/jour/article/view/469 |
| work_keys_str_mv | AT vvsaushkin assessmentofaccuracyincalculatinghemodynamicparametersandleftventricularmassaccordingtoecgsynchronizedmyocardialperfusionscintigraphicdatacomparisonwithcardiacmultislicecomputedtomography AT kvzavadovskiy assessmentofaccuracyincalculatinghemodynamicparametersandleftventricularmassaccordingtoecgsynchronizedmyocardialperfusionscintigraphicdatacomparisonwithcardiacmultislicecomputedtomography |