Clinical outcome of vertebroplasty alone versus short-segment posterior instrumentation with vertebroplasty in osteoporotic vertebral fracture: a propensity-score-matched analysis

Study Design Retrospective cohort study with propensity-score-matched analysis. Purpose To compare the efficacy of vertebroplasty (VP) versus short-segment posterior instrumentation (SS) with VP in patients with osteoporotic vertebral fractures (OVFs). Overview of Literature OVFs significantly affec...

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Main Authors: Borriwat Santipas, Nath Adulkasem, Korawish Mekariya, Ekkapoj Korwutthikulrangsri, Monchai Ruangchainikom, Werasak Sutipornplalangkul
Format: Article
Language:English
Published: Korean Spine Society 2025-02-01
Series:Asian Spine Journal
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Online Access:http://asianspinejournal.org/upload/pdf/asj-2024-0231.pdf
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author Borriwat Santipas
Nath Adulkasem
Korawish Mekariya
Ekkapoj Korwutthikulrangsri
Monchai Ruangchainikom
Werasak Sutipornplalangkul
author_facet Borriwat Santipas
Nath Adulkasem
Korawish Mekariya
Ekkapoj Korwutthikulrangsri
Monchai Ruangchainikom
Werasak Sutipornplalangkul
author_sort Borriwat Santipas
collection DOAJ
description Study Design Retrospective cohort study with propensity-score-matched analysis. Purpose To compare the efficacy of vertebroplasty (VP) versus short-segment posterior instrumentation (SS) with VP in patients with osteoporotic vertebral fractures (OVFs). Overview of Literature OVFs significantly affect the aging population, causing pain, reduced mobility, and increased dependence. Treatment guidelines vary, and a consensus on the most effective approach remains unclear. To the best of our knowledge, no previous report focused on the efficacy comparison of VP alone versus SS with VP. Methods The study included patients with OVFs undergoing VP with or without SS from 2017 to 2021. Baseline demographic and patient-reported outcome scores, including Oswestry Disability Index (ODI) and European Quality-of-Life-5 Dimensions (EQ-5D), were collected preoperatively and 1 year postoperatively. Radiographic outcomes, including Cobb angle, sagittal angle reduction, and kyphotic progression, were assessed. Perioperative data were gathered. Propensity-score matching was conducted to compare both groups after adjusting for baseline characteristics. Results This study included 60 patients. The subsequent analyses included 19 patients in both the SS+VP group and the VP groups after matching patient cohorts across various covariates. The SS+VP group demonstrated better ODI (30.38±17.12 vs. 49.68±19.43, p=0.0025) and EQ-5D scores (0.80±0.19 vs. 0.6±0.31, p=0.0018) at 1 year postoperative. Sagittal angle correction was higher in the SS+VP group (10.63°±6.34° vs. 5.74°±5.91°, p=0.0188). The SS+VP group exhibited higher blood loss and longer operative time. Perioperative complications, kyphotic progression, adjacent fractures, and reoperation rates were similar between the two groups. Conclusions SS with VP generated superior patient-reported outcomes and sagittal angle correction for OVFs when evaluated one year postoperatively compared to VP alone. Perioperative complications, kyphotic progression, adjacent fractures, and reoperation rates were similar despite increased blood loss and extended operative time.
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1976-7846
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spelling doaj-art-e8cf11867e7f4020b33bf621bf34c8eb2025-08-20T02:32:14ZengKorean Spine SocietyAsian Spine Journal1976-19021976-78462025-02-01191283710.31616/asj.2024.02311703Clinical outcome of vertebroplasty alone versus short-segment posterior instrumentation with vertebroplasty in osteoporotic vertebral fracture: a propensity-score-matched analysisBorriwat SantipasNath AdulkasemKorawish MekariyaEkkapoj KorwutthikulrangsriMonchai RuangchainikomWerasak SutipornplalangkulStudy Design Retrospective cohort study with propensity-score-matched analysis. Purpose To compare the efficacy of vertebroplasty (VP) versus short-segment posterior instrumentation (SS) with VP in patients with osteoporotic vertebral fractures (OVFs). Overview of Literature OVFs significantly affect the aging population, causing pain, reduced mobility, and increased dependence. Treatment guidelines vary, and a consensus on the most effective approach remains unclear. To the best of our knowledge, no previous report focused on the efficacy comparison of VP alone versus SS with VP. Methods The study included patients with OVFs undergoing VP with or without SS from 2017 to 2021. Baseline demographic and patient-reported outcome scores, including Oswestry Disability Index (ODI) and European Quality-of-Life-5 Dimensions (EQ-5D), were collected preoperatively and 1 year postoperatively. Radiographic outcomes, including Cobb angle, sagittal angle reduction, and kyphotic progression, were assessed. Perioperative data were gathered. Propensity-score matching was conducted to compare both groups after adjusting for baseline characteristics. Results This study included 60 patients. The subsequent analyses included 19 patients in both the SS+VP group and the VP groups after matching patient cohorts across various covariates. The SS+VP group demonstrated better ODI (30.38±17.12 vs. 49.68±19.43, p=0.0025) and EQ-5D scores (0.80±0.19 vs. 0.6±0.31, p=0.0018) at 1 year postoperative. Sagittal angle correction was higher in the SS+VP group (10.63°±6.34° vs. 5.74°±5.91°, p=0.0188). The SS+VP group exhibited higher blood loss and longer operative time. Perioperative complications, kyphotic progression, adjacent fractures, and reoperation rates were similar between the two groups. Conclusions SS with VP generated superior patient-reported outcomes and sagittal angle correction for OVFs when evaluated one year postoperatively compared to VP alone. Perioperative complications, kyphotic progression, adjacent fractures, and reoperation rates were similar despite increased blood loss and extended operative time.http://asianspinejournal.org/upload/pdf/asj-2024-0231.pdfvertebroplastyspinal instrumentationosteoporosisfracturesspine
spellingShingle Borriwat Santipas
Nath Adulkasem
Korawish Mekariya
Ekkapoj Korwutthikulrangsri
Monchai Ruangchainikom
Werasak Sutipornplalangkul
Clinical outcome of vertebroplasty alone versus short-segment posterior instrumentation with vertebroplasty in osteoporotic vertebral fracture: a propensity-score-matched analysis
Asian Spine Journal
vertebroplasty
spinal instrumentation
osteoporosis
fractures
spine
title Clinical outcome of vertebroplasty alone versus short-segment posterior instrumentation with vertebroplasty in osteoporotic vertebral fracture: a propensity-score-matched analysis
title_full Clinical outcome of vertebroplasty alone versus short-segment posterior instrumentation with vertebroplasty in osteoporotic vertebral fracture: a propensity-score-matched analysis
title_fullStr Clinical outcome of vertebroplasty alone versus short-segment posterior instrumentation with vertebroplasty in osteoporotic vertebral fracture: a propensity-score-matched analysis
title_full_unstemmed Clinical outcome of vertebroplasty alone versus short-segment posterior instrumentation with vertebroplasty in osteoporotic vertebral fracture: a propensity-score-matched analysis
title_short Clinical outcome of vertebroplasty alone versus short-segment posterior instrumentation with vertebroplasty in osteoporotic vertebral fracture: a propensity-score-matched analysis
title_sort clinical outcome of vertebroplasty alone versus short segment posterior instrumentation with vertebroplasty in osteoporotic vertebral fracture a propensity score matched analysis
topic vertebroplasty
spinal instrumentation
osteoporosis
fractures
spine
url http://asianspinejournal.org/upload/pdf/asj-2024-0231.pdf
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