Recombinant tissue plasminogen activator protects neurons after intracerebral hemorrhage through activating the PI3K/AKT/mTOR pathway

Recombinant tissue plasminogen activator protects neurons after intracerebral hemorrhage through activating the PI3K/AKT/mTOR pathway

Recombinant tissue plasminogen activator is commonly used for hematoma evacuation in minimally invasive surgery following intracerebral hemorrhage. However, during minimally invasive surgery, recombinant tissue plasminogen activator may come into contact with brain tissue. Therefore, a thorough asse...

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Bibliographic Details
Main Authors: Jie Jing, Shiling Chen, Xuan Wu, Jingfei Yang, Xia Liu, Jiahui Wang, Jingyi Wang, Yunjie Li, Ping Zhang, Zhouping Tang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2026-04-01
Series:Neural Regeneration Research
Subjects:
apoptosis
autophagy
endoplasmic reticulum stress
epidermal growth factor
intracerebral hemorrhage
mammalian target of rapamycin
minimally invasive surgery
phosphoinositide 3-kinase
rac-alpha serine/threonine-protein kinase
recombinant tissue plasminogen activator
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-23-01953
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