Identifying new targets for improving terpenoid biosynthesis in Yarrowia lipolytica through random genomic cytosine base editing
Abstract Background Genome-scale mutagenesis integrated with high-throughput phenotypic screening and causal mutation mapping serves as a robust paradigm for systemic genetic dissection. Despite the application of non-homologous end joining (NHEJ)-mediated genome editing in Yarrowia lipolytica, the...
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| Main Authors: | Zhenxia Li, Bo Liu, Rongtao Lv, Zhe Sun, QingYan Li, XueLi Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | Microbial Cell Factories |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12934-025-02819-5 |
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