Design of Fe<sub>7</sub>S<sub>8</sub>@Lip Composite for the pH-Selective and Magnetically Targeted Programmed Release of H<sub>2</sub>S

The significance of hydrogen sulfide (H<sub>2</sub>S) release in vivo is multifaceted. It functions as a crucial gaseous signaling molecule with extensive physiological and pathological impacts within organisms. To create novel H<sub>2</sub>S-releasing materials, we synthesiz...

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Main Authors: Shenghua Wang, Hanlin Wei, Jialian Li, Ning Liu, Zhiming Deng, Junqing Huang
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Magnetochemistry
Subjects:
Online Access:https://www.mdpi.com/2312-7481/11/3/22
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author Shenghua Wang
Hanlin Wei
Jialian Li
Ning Liu
Zhiming Deng
Junqing Huang
author_facet Shenghua Wang
Hanlin Wei
Jialian Li
Ning Liu
Zhiming Deng
Junqing Huang
author_sort Shenghua Wang
collection DOAJ
description The significance of hydrogen sulfide (H<sub>2</sub>S) release in vivo is multifaceted. It functions as a crucial gaseous signaling molecule with extensive physiological and pathological impacts within organisms. To create novel H<sub>2</sub>S-releasing materials, we synthesized Fe<sub>7</sub>S<sub>8</sub>@Lip, a slow-release gas nanocomposite, which exhibits stable and sustained H<sub>2</sub>S-release properties. Our gas releaser possesses selective H<sub>2</sub>S-release capabilities, and, notably, it can achieve effective H<sub>2</sub>S release under magnetic force with the assistance of a magnetic field. In conclusion, our findings indicate that Fe<sub>7</sub>S<sub>8</sub>@Lip can serve as an H<sub>2</sub>S slow-release nanocomposite, offering a potentially innovative approach for programmed H<sub>2</sub>S release in vivo.
format Article
id doaj-art-e8c82b12a24d4e42ae5edd9029a7dfb6
institution OA Journals
issn 2312-7481
language English
publishDate 2025-03-01
publisher MDPI AG
record_format Article
series Magnetochemistry
spelling doaj-art-e8c82b12a24d4e42ae5edd9029a7dfb62025-08-20T01:49:00ZengMDPI AGMagnetochemistry2312-74812025-03-011132210.3390/magnetochemistry11030022Design of Fe<sub>7</sub>S<sub>8</sub>@Lip Composite for the pH-Selective and Magnetically Targeted Programmed Release of H<sub>2</sub>SShenghua Wang0Hanlin Wei1Jialian Li2Ning Liu3Zhiming Deng4Junqing Huang5School of Chemical and Environmental Engineering, Hunan Institute of Technology, Hengyang 421010, ChinaState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, ChinaState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, ChinaSchool of Chemical and Environmental Engineering, Hunan Institute of Technology, Hengyang 421010, ChinaState Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, ChinaNational Key Laboratory of Macromolecular Drug Development and Manufacturing, School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou 325035, ChinaThe significance of hydrogen sulfide (H<sub>2</sub>S) release in vivo is multifaceted. It functions as a crucial gaseous signaling molecule with extensive physiological and pathological impacts within organisms. To create novel H<sub>2</sub>S-releasing materials, we synthesized Fe<sub>7</sub>S<sub>8</sub>@Lip, a slow-release gas nanocomposite, which exhibits stable and sustained H<sub>2</sub>S-release properties. Our gas releaser possesses selective H<sub>2</sub>S-release capabilities, and, notably, it can achieve effective H<sub>2</sub>S release under magnetic force with the assistance of a magnetic field. In conclusion, our findings indicate that Fe<sub>7</sub>S<sub>8</sub>@Lip can serve as an H<sub>2</sub>S slow-release nanocomposite, offering a potentially innovative approach for programmed H<sub>2</sub>S release in vivo.https://www.mdpi.com/2312-7481/11/3/22magnetically targetedH<sub>2</sub>SFe<sub>7</sub>S<sub>8</sub>@LippH-selective
spellingShingle Shenghua Wang
Hanlin Wei
Jialian Li
Ning Liu
Zhiming Deng
Junqing Huang
Design of Fe<sub>7</sub>S<sub>8</sub>@Lip Composite for the pH-Selective and Magnetically Targeted Programmed Release of H<sub>2</sub>S
Magnetochemistry
magnetically targeted
H<sub>2</sub>S
Fe<sub>7</sub>S<sub>8</sub>@Lip
pH-selective
title Design of Fe<sub>7</sub>S<sub>8</sub>@Lip Composite for the pH-Selective and Magnetically Targeted Programmed Release of H<sub>2</sub>S
title_full Design of Fe<sub>7</sub>S<sub>8</sub>@Lip Composite for the pH-Selective and Magnetically Targeted Programmed Release of H<sub>2</sub>S
title_fullStr Design of Fe<sub>7</sub>S<sub>8</sub>@Lip Composite for the pH-Selective and Magnetically Targeted Programmed Release of H<sub>2</sub>S
title_full_unstemmed Design of Fe<sub>7</sub>S<sub>8</sub>@Lip Composite for the pH-Selective and Magnetically Targeted Programmed Release of H<sub>2</sub>S
title_short Design of Fe<sub>7</sub>S<sub>8</sub>@Lip Composite for the pH-Selective and Magnetically Targeted Programmed Release of H<sub>2</sub>S
title_sort design of fe sub 7 sub s sub 8 sub lip composite for the ph selective and magnetically targeted programmed release of h sub 2 sub s
topic magnetically targeted
H<sub>2</sub>S
Fe<sub>7</sub>S<sub>8</sub>@Lip
pH-selective
url https://www.mdpi.com/2312-7481/11/3/22
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