Aregs-IGFBP3-mediated SMC-like cells apoptosis impairs beige adipocytes formation in aged mice

Aregs-IGFBP3-mediated SMC-like cells apoptosis impairs beige adipocytes formation in aged mice

Aging is associated with a decline in the browning capacity of white adipose tissue (WAT), contributing to metabolic dysfunction. Beige adipocytes, which dissipate excess energy as heat, are a key feature of this process. In this study, we investigate the role of adipose stem and progenitor cells (A...

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Bibliographic Details
Main Authors: Shifeng Wang, Yuanxu Cui, Limei Wang, Chun Feng, Yifei Sun, Bangyun Huo, Honglu Jiang, Mingyu Zhao, Yingying Tu, Qiyue Wang, Yutao Yang, Qiang Zhang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Molecular Metabolism
Subjects:
Aregs
IGFBP3
SMC-Like cells
Browning
Aging
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877825000328
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