Progressive Macular Hypomelanosis: A Rarely Diagnosed Hypopigmentation in Caucasians

A 35-year-old woman who developed whitish macules on trunk and limbs at 12 years of age and observed a remarkable increase of the hypopigmentated lesions after her pregnancies at ages 29 and 32 years. Because of the highly characteristic clinical aspect and the light- and electron-microscopic histop...

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Main Authors: Sven Neynaber, Christina Kirschner, Stefanie Kamann, Gerd Plewig, Michael J. Flaig
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Dermatology Research and Practice
Online Access:http://dx.doi.org/10.1155/2009/607682
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author Sven Neynaber
Christina Kirschner
Stefanie Kamann
Gerd Plewig
Michael J. Flaig
author_facet Sven Neynaber
Christina Kirschner
Stefanie Kamann
Gerd Plewig
Michael J. Flaig
author_sort Sven Neynaber
collection DOAJ
description A 35-year-old woman who developed whitish macules on trunk and limbs at 12 years of age and observed a remarkable increase of the hypopigmentated lesions after her pregnancies at ages 29 and 32 years. Because of the highly characteristic clinical aspect and the light- and electron-microscopic histopathologic findings, we diagnosed progressive macular hypomelanosis (PMH). It is a nonscaly disorder with hypopigmented macules mainly on the trunk and is more often seen in young women. In contrast to some authors assuming the presence of Propionibacterium spp. as a matter of principle in PMH, we report a case with no evidence for Propionibacterium spp.
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publishDate 2009-01-01
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series Dermatology Research and Practice
spelling doaj-art-e8c5604d20a14b8482d8632c99d922a52025-08-20T03:21:10ZengWileyDermatology Research and Practice1687-61051687-61132009-01-01200910.1155/2009/607682607682Progressive Macular Hypomelanosis: A Rarely Diagnosed Hypopigmentation in CaucasiansSven Neynaber0Christina Kirschner1Stefanie Kamann2Gerd Plewig3Michael J. Flaig4Department of Dermatology and Allergology, Ludwig-Maximilians University, Frauenlobstrasse 9-11, DE-80337 Munich, GermanyDepartment of Dermatology and Allergology, Ludwig-Maximilians University, Frauenlobstrasse 9-11, DE-80337 Munich, GermanyDepartment of Dermatology and Allergology, Ludwig-Maximilians University, Frauenlobstrasse 9-11, DE-80337 Munich, GermanyDepartment of Dermatology and Allergology, Ludwig-Maximilians University, Frauenlobstrasse 9-11, DE-80337 Munich, GermanyDepartment of Dermatology and Allergology, Ludwig-Maximilians University, Frauenlobstrasse 9-11, DE-80337 Munich, GermanyA 35-year-old woman who developed whitish macules on trunk and limbs at 12 years of age and observed a remarkable increase of the hypopigmentated lesions after her pregnancies at ages 29 and 32 years. Because of the highly characteristic clinical aspect and the light- and electron-microscopic histopathologic findings, we diagnosed progressive macular hypomelanosis (PMH). It is a nonscaly disorder with hypopigmented macules mainly on the trunk and is more often seen in young women. In contrast to some authors assuming the presence of Propionibacterium spp. as a matter of principle in PMH, we report a case with no evidence for Propionibacterium spp.http://dx.doi.org/10.1155/2009/607682
spellingShingle Sven Neynaber
Christina Kirschner
Stefanie Kamann
Gerd Plewig
Michael J. Flaig
Progressive Macular Hypomelanosis: A Rarely Diagnosed Hypopigmentation in Caucasians
Dermatology Research and Practice
title Progressive Macular Hypomelanosis: A Rarely Diagnosed Hypopigmentation in Caucasians
title_full Progressive Macular Hypomelanosis: A Rarely Diagnosed Hypopigmentation in Caucasians
title_fullStr Progressive Macular Hypomelanosis: A Rarely Diagnosed Hypopigmentation in Caucasians
title_full_unstemmed Progressive Macular Hypomelanosis: A Rarely Diagnosed Hypopigmentation in Caucasians
title_short Progressive Macular Hypomelanosis: A Rarely Diagnosed Hypopigmentation in Caucasians
title_sort progressive macular hypomelanosis a rarely diagnosed hypopigmentation in caucasians
url http://dx.doi.org/10.1155/2009/607682
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