SIRT1 Mediates Neuropathic Pain Induced by Sciatic Nerve Chronic Constrictive Injury in the VTA-NAc Pathway
Background. Mounting evidence has shown that sirtuin 1 (SIRT1), a class III histone deacetylase, alleviated several types of neuropathic pain in the spinal cord and dorsal root ganglion and regulated some aberrant behaviors in the ventral tegmental area (VTA) and the nucleus accumbens (NAc). Methods...
Saved in:
| Main Authors: | Yangyang Li, Lei Wang, Guotao Zhang, Xueli Qiao, Mingxing Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2020/4245968 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Measurement of neuropathic pain in constrictive sciatic nerve models in rats
by: José R. Carrillo-Márquez, et al.
Published: (2025-04-01) -
Effect of Electroacupuncture on Rats with Chronic Constriction Injury-Induced Neuropathic Pain
by: Hsin-Cheng Hsu, et al.
Published: (2014-01-01) -
VTA dopaminergic neurons involved in chronic spared nerve injury pain-induced depressive-like behavior
by: Ludi Zhang, et al.
Published: (2025-03-01) -
Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway.
by: Ismail Badshah, et al.
Published: (2023-01-01) -
Expression of Concern: Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway.
by: PLOS One Editors
Published: (2025-01-01)