Learning the Lessons of Antitumour Necrosis Factor Therapy-Associated Psoriasis

Psoriasis or psoriasiform skin lesions, as an adverse effect of treatment with antitumor necrosis factor antibody therapy, have been described relatively recently. Patients with these lesions have no personal or family history of psoriasis. In a small number of cases, an association with Chlamydia h...

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Main Authors: Matt Shale, Subrata Ghosh
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2009/514618
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author Matt Shale
Subrata Ghosh
author_facet Matt Shale
Subrata Ghosh
author_sort Matt Shale
collection DOAJ
description Psoriasis or psoriasiform skin lesions, as an adverse effect of treatment with antitumor necrosis factor antibody therapy, have been described relatively recently. Patients with these lesions have no personal or family history of psoriasis. In a small number of cases, an association with Chlamydia has been suggested. The skin lesions may disappear on discontinuation of therapy or, in the majority of cases, even if antitumor necrosis factor antibody therapy is continued. Therefore, withdrawal of therapy is generally not required for this adverse effect but referral to a dermatologist may be desirable for confirmation of diagnosis and treatment.
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spelling doaj-art-e8bf22b5884e491485839a7890195d342025-08-20T03:21:09ZengWileyCanadian Journal of Gastroenterology0835-79002009-01-01231067467610.1155/2009/514618Learning the Lessons of Antitumour Necrosis Factor Therapy-Associated PsoriasisMatt Shale0Subrata Ghosh1Gastroenterology Section, Imperial College London, Hammersmith Hospital, London, UKUniversity of Calgary, Calgary, Alberta, CanadaPsoriasis or psoriasiform skin lesions, as an adverse effect of treatment with antitumor necrosis factor antibody therapy, have been described relatively recently. Patients with these lesions have no personal or family history of psoriasis. In a small number of cases, an association with Chlamydia has been suggested. The skin lesions may disappear on discontinuation of therapy or, in the majority of cases, even if antitumor necrosis factor antibody therapy is continued. Therefore, withdrawal of therapy is generally not required for this adverse effect but referral to a dermatologist may be desirable for confirmation of diagnosis and treatment.http://dx.doi.org/10.1155/2009/514618
spellingShingle Matt Shale
Subrata Ghosh
Learning the Lessons of Antitumour Necrosis Factor Therapy-Associated Psoriasis
Canadian Journal of Gastroenterology
title Learning the Lessons of Antitumour Necrosis Factor Therapy-Associated Psoriasis
title_full Learning the Lessons of Antitumour Necrosis Factor Therapy-Associated Psoriasis
title_fullStr Learning the Lessons of Antitumour Necrosis Factor Therapy-Associated Psoriasis
title_full_unstemmed Learning the Lessons of Antitumour Necrosis Factor Therapy-Associated Psoriasis
title_short Learning the Lessons of Antitumour Necrosis Factor Therapy-Associated Psoriasis
title_sort learning the lessons of antitumour necrosis factor therapy associated psoriasis
url http://dx.doi.org/10.1155/2009/514618
work_keys_str_mv AT mattshale learningthelessonsofantitumournecrosisfactortherapyassociatedpsoriasis
AT subrataghosh learningthelessonsofantitumournecrosisfactortherapyassociatedpsoriasis