Designing and evaluation of the effect of community-based intervention on breast self-examination among reproductive-aged women in Ethiopia: A Cluster Randomized Controlled Trial.

<h4>Background</h4>Though early intervention saves many lives worldwide, breast cancer remains a leading cause of cancer among women in Ethiopia. This study, therefore, aimed to evaluate community-based interventions promoting breast self-examination using the Health Belief Model.<h4&...

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Main Authors: Feleke Doyore Agide, Gholamreza Garmaroudi, Roya Sadeghi, Elham Shakibazadeh, Mehdi Yaseri, Zewdie Birhanu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0329839
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Summary:<h4>Background</h4>Though early intervention saves many lives worldwide, breast cancer remains a leading cause of cancer among women in Ethiopia. This study, therefore, aimed to evaluate community-based interventions promoting breast self-examination using the Health Belief Model.<h4>Methods</h4>A cluster randomized controlled trial followed by a cross-sectional study lasting six months was used to evaluate the effectiveness of the community-based educational intervention on breast self-examination among reproductive-aged women in Ethiopia. A total of 810 participants were randomly assigned in a 1:1 ratio and assessed at baseline, three months, and six months post-intervention. A general linear model for repeated measures was used to examine the mean differences in study variables across time points. Non-parametric tests (Cochran's Q) were employed to analyze dichotomous variables related to breast self-examination practices. Path analysis was conducted to examine the interactions among the constructs of the Health Belief Model.<h4>Results</h4>A total of 810 reproductive-aged women participated in the study, yielding a 100% response rate at baseline. The mean age of participants was 33.2 ± 7.7 years in the intervention group and 33.5 ± 8.1 years in the control group. The proportion of women performing breast self-examinations increased from 33.3% at baseline to 59.9% at the end of the intervention. And the Comprehensive knowledge about breast self-examination rose from 11.7% to 69.1% over the same period. Perceived susceptibility, perceived severity, knowledge, and health motivations had a statistically significant mean difference between the intervention and control groups (p < 0.0001). We registered PACTR database (https://pactr.samrc.ac.za/): "PACTR201802002902886".<h4>Conclusions</h4>The study found that there is a strong interplay between the likelihood of performing breast self-examination and perceived susceptibility, perceived severity, knowledge, and health motivations. Field specialists should figure out the problem related to perception and awareness through intensive health promotion interventions.<h4>Trial registration</h4>Registered in the Pan African Clinical Trial Registry (www.pactr.org) database, and the unique identification number for the registry is PACTR201802002902886.
ISSN:1932-6203