Pantoea sp. Isolated from Tropical Fresh Water Exhibiting N-Acyl Homoserine Lactone Production

N-Acyl homoserine lactone (AHL) serves as signaling molecule for quorum sensing (QS) in Gram-negative bacteria to regulate various physiological activities including pathogenicity. With the aim of isolating freshwater-borne bacteria that can cause outbreak of disease in plants and portrayed QS prope...

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Main Authors: Wen-Si Tan, Nina Yusrina Muhamad Yunos, Pui-Wan Tan, Nur Izzati Mohamad, Tan-Guan-Sheng Adrian, Wai-Fong Yin, Kok-Gan Chan
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/828971
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author Wen-Si Tan
Nina Yusrina Muhamad Yunos
Pui-Wan Tan
Nur Izzati Mohamad
Tan-Guan-Sheng Adrian
Wai-Fong Yin
Kok-Gan Chan
author_facet Wen-Si Tan
Nina Yusrina Muhamad Yunos
Pui-Wan Tan
Nur Izzati Mohamad
Tan-Guan-Sheng Adrian
Wai-Fong Yin
Kok-Gan Chan
author_sort Wen-Si Tan
collection DOAJ
description N-Acyl homoserine lactone (AHL) serves as signaling molecule for quorum sensing (QS) in Gram-negative bacteria to regulate various physiological activities including pathogenicity. With the aim of isolating freshwater-borne bacteria that can cause outbreak of disease in plants and portrayed QS properties, environmental water sampling was conducted. Here we report the preliminary screening of AHL production using Chromobacterium violaceum CV026 and Escherichia coli [pSB401] as AHL biosensors. The 16S rDNA gene sequence of isolate M009 showed the highest sequence similarity to Pantoea stewartii S9-116, which is a plant pathogen. The isolated Pantoea sp. was confirmed to produce N-3-oxohexanoyl-L-HSL (3-oxo-C6-HSL) through analysis of high resolution mass tandem mass spectrometry.
format Article
id doaj-art-e8b286a3c8444aebb63b22ff274e67e9
institution OA Journals
issn 2356-6140
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language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-e8b286a3c8444aebb63b22ff274e67e92025-08-20T02:22:01ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/828971828971Pantoea sp. Isolated from Tropical Fresh Water Exhibiting N-Acyl Homoserine Lactone ProductionWen-Si Tan0Nina Yusrina Muhamad Yunos1Pui-Wan Tan2Nur Izzati Mohamad3Tan-Guan-Sheng Adrian4Wai-Fong Yin5Kok-Gan Chan6Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, MalaysiaDivision of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, MalaysiaDivision of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, MalaysiaDivision of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, MalaysiaDivision of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, MalaysiaDivision of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, MalaysiaDivision of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, MalaysiaN-Acyl homoserine lactone (AHL) serves as signaling molecule for quorum sensing (QS) in Gram-negative bacteria to regulate various physiological activities including pathogenicity. With the aim of isolating freshwater-borne bacteria that can cause outbreak of disease in plants and portrayed QS properties, environmental water sampling was conducted. Here we report the preliminary screening of AHL production using Chromobacterium violaceum CV026 and Escherichia coli [pSB401] as AHL biosensors. The 16S rDNA gene sequence of isolate M009 showed the highest sequence similarity to Pantoea stewartii S9-116, which is a plant pathogen. The isolated Pantoea sp. was confirmed to produce N-3-oxohexanoyl-L-HSL (3-oxo-C6-HSL) through analysis of high resolution mass tandem mass spectrometry.http://dx.doi.org/10.1155/2014/828971
spellingShingle Wen-Si Tan
Nina Yusrina Muhamad Yunos
Pui-Wan Tan
Nur Izzati Mohamad
Tan-Guan-Sheng Adrian
Wai-Fong Yin
Kok-Gan Chan
Pantoea sp. Isolated from Tropical Fresh Water Exhibiting N-Acyl Homoserine Lactone Production
The Scientific World Journal
title Pantoea sp. Isolated from Tropical Fresh Water Exhibiting N-Acyl Homoserine Lactone Production
title_full Pantoea sp. Isolated from Tropical Fresh Water Exhibiting N-Acyl Homoserine Lactone Production
title_fullStr Pantoea sp. Isolated from Tropical Fresh Water Exhibiting N-Acyl Homoserine Lactone Production
title_full_unstemmed Pantoea sp. Isolated from Tropical Fresh Water Exhibiting N-Acyl Homoserine Lactone Production
title_short Pantoea sp. Isolated from Tropical Fresh Water Exhibiting N-Acyl Homoserine Lactone Production
title_sort pantoea sp isolated from tropical fresh water exhibiting n acyl homoserine lactone production
url http://dx.doi.org/10.1155/2014/828971
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