Parental kynurenine 3-monooxygenase genotype in mice directs sex-specific behavioral outcomes in offspring

Parental kynurenine 3-monooxygenase genotype in mice directs sex-specific behavioral outcomes in offspring

Abstract Background Disruptions in brain development can impact behavioral traits and increase the risk of neurodevelopmental conditions such as autism spectrum disorder, attention-deficit/hyperactivity disorder (ADHD), schizophrenia, and bipolar disorder, often in sex-specific ways. Dysregulation o...

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Bibliographic Details
Main Authors: Snezana Milosavljevic, Maria V. Piroli, Emma J. Sandago, Gerardo G. Piroli, Holland H. Smith, Sarah Beggiato, Norma Frizzell, Ana Pocivavsek
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Biology of Sex Differences
Subjects:
Kynurenine pathway
Neurodevelopment
Sleep
Cognition
Parental genotype
Online Access:https://doi.org/10.1186/s13293-025-00703-w
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