Embryoid body-based differentiation of human-induced pluripotent stem cells into cells with a corneal stromal keratocyte phenotype
Objective The transparency of the cornea is determined by the extracellular matrix, which is secreted by corneal stromal keratocytes (CSKs). Human-induced pluripotent stem cell (hiPSC)-derived keratocytes (hiPSC-CSKs) can be used in cell-based therapy for treating corneal blindness. Our goal was to...
Saved in:
| Main Authors: | Qian Li, Jie Chen, Yifan Liu, Qingjian Ou, Tingting Cui, Huimin Yang, Jiancen Tang, Lixia Lu, Guotong Xu, Hongping Cui, Caixia Jin |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2024-12-01
|
| Series: | BMJ Open Ophthalmology |
| Online Access: | https://bmjophth.bmj.com/content/9/1/e001828.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Co-differentiation and enrichment of corneal endothelial cells and keratocytes from human pluripotent stem cells
by: Abhinav Reddy Kethiri, et al.
Published: (2025-05-01) -
Advances in Regulatory Strategies of Differentiating Stem Cells towards Keratocytes
by: Aini Zhang, et al.
Published: (2022-01-01) -
Effect of Decorin and Aligned Collagen Fibril Topography on TGF-β1 Activation of Corneal Keratocytes
by: Nathaniel S. Tjahjono, et al.
Published: (2025-03-01) -
Protocol for generating human cerebral organoids from two-dimensional cultures of pluripotent stem cells bypassing embryoid body aggregation
by: Rosa González-Sastre, et al.
Published: (2025-03-01) -
Changes in Corneal Keratocytes and Collagen Fibrils as an Indicator of Keratoconus Onset: A Preliminary Study Based on OCT Subchannel Images
by: Frederick H Silver, et al.
Published: (2025-06-01)