Incidence Trends of Rheumatoid Arthritis in Korea for 11 Years (2006–2017)
Background/Objectives: Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized by joint damage. However, no incidence analyses have been conducted on a Korean population since 2013. We aimed to calculate the incidence of RA and examine trends using complete Korean National Health...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-11-01
|
| Series: | Clinics and Practice |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2039-7283/14/6/193 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850041940335132672 |
|---|---|
| author | Hanna Lee Sang-Il Lee Hyunjin Lim Hyun-Ok Kim Rock Bum Kim Yun-Hong Cheon |
| author_facet | Hanna Lee Sang-Il Lee Hyunjin Lim Hyun-Ok Kim Rock Bum Kim Yun-Hong Cheon |
| author_sort | Hanna Lee |
| collection | DOAJ |
| description | Background/Objectives: Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized by joint damage. However, no incidence analyses have been conducted on a Korean population since 2013. We aimed to calculate the incidence of RA and examine trends using complete Korean National Health Insurance Service claims data from 2007. Methods: We used 16 years of Korean NHIS claims data from 1 January 2002 to 31 December 2017. Patients were defined as having RA when diagnosed with ICD-10 codes M05 and M06. We set the 5-year period prior to 2006 as disease-free. Results: From 2007 to 2017, the incidence rate of RA was 35 to 43 per 100,000 individuals. The female-to-male ratio was approximately 3–3.5 to 1. The sex-standardized incidence rate was highest in the 60–69 age group but gradually declined, resulting in a reversal in 2017, with the highest incidence rate observed in the 50–59 age group. The incidence of elderly onset RA (EORA) in individuals aged >60 years exhibited a decreasing trend during the study period (age 60–69, −6.45, 95% CI = −8.27 to −4.62, <i>p</i> < 0.001; age ≥70, −6.09, 95% CI = −7.66 to −4.53, <i>p</i> < 0.001). Conclusions: This study is the first to analyze the incidence trend of RA over an 11-year period. In South Korea, the incidence of RA has shown a decreasing trend since 2011; the same trend was observed in the EORA group. Young-onset RA showed the opposite trend, suggesting that RA is diagnosed earlier, due to the new RA classification criteria. |
| format | Article |
| id | doaj-art-e8a1e7b1ac8b45368546fa53a7556066 |
| institution | DOAJ |
| issn | 2039-7283 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Clinics and Practice |
| spelling | doaj-art-e8a1e7b1ac8b45368546fa53a75560662025-08-20T02:55:40ZengMDPI AGClinics and Practice2039-72832024-11-011462475248310.3390/clinpract14060193Incidence Trends of Rheumatoid Arthritis in Korea for 11 Years (2006–2017)Hanna Lee0Sang-Il Lee1Hyunjin Lim2Hyun-Ok Kim3Rock Bum Kim4Yun-Hong Cheon5Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University Hospital, Changwon 51472, Republic of KoreaDivision of Rheumatology, Department of Internal Medicine, Gyeongsang National University Hospital, Jinju 52727, Republic of KoreaDivision of Rheumatology, Department of Internal Medicine, Gyeongsang National University Hospital, Jinju 52727, Republic of KoreaDivision of Rheumatology, Department of Internal Medicine, Gyeongsang National University Hospital, Changwon 51472, Republic of KoreaRegional Cardiocerebrovascular Disease Center, Gyeongsang National University Hospital, Jinju 52727, Republic of KoreaDivision of Rheumatology, Department of Internal Medicine, Gyeongsang National University Hospital, Jinju 52727, Republic of KoreaBackground/Objectives: Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized by joint damage. However, no incidence analyses have been conducted on a Korean population since 2013. We aimed to calculate the incidence of RA and examine trends using complete Korean National Health Insurance Service claims data from 2007. Methods: We used 16 years of Korean NHIS claims data from 1 January 2002 to 31 December 2017. Patients were defined as having RA when diagnosed with ICD-10 codes M05 and M06. We set the 5-year period prior to 2006 as disease-free. Results: From 2007 to 2017, the incidence rate of RA was 35 to 43 per 100,000 individuals. The female-to-male ratio was approximately 3–3.5 to 1. The sex-standardized incidence rate was highest in the 60–69 age group but gradually declined, resulting in a reversal in 2017, with the highest incidence rate observed in the 50–59 age group. The incidence of elderly onset RA (EORA) in individuals aged >60 years exhibited a decreasing trend during the study period (age 60–69, −6.45, 95% CI = −8.27 to −4.62, <i>p</i> < 0.001; age ≥70, −6.09, 95% CI = −7.66 to −4.53, <i>p</i> < 0.001). Conclusions: This study is the first to analyze the incidence trend of RA over an 11-year period. In South Korea, the incidence of RA has shown a decreasing trend since 2011; the same trend was observed in the EORA group. Young-onset RA showed the opposite trend, suggesting that RA is diagnosed earlier, due to the new RA classification criteria.https://www.mdpi.com/2039-7283/14/6/193rheumatoid arthritisincidenceautoimmune disease |
| spellingShingle | Hanna Lee Sang-Il Lee Hyunjin Lim Hyun-Ok Kim Rock Bum Kim Yun-Hong Cheon Incidence Trends of Rheumatoid Arthritis in Korea for 11 Years (2006–2017) Clinics and Practice rheumatoid arthritis incidence autoimmune disease |
| title | Incidence Trends of Rheumatoid Arthritis in Korea for 11 Years (2006–2017) |
| title_full | Incidence Trends of Rheumatoid Arthritis in Korea for 11 Years (2006–2017) |
| title_fullStr | Incidence Trends of Rheumatoid Arthritis in Korea for 11 Years (2006–2017) |
| title_full_unstemmed | Incidence Trends of Rheumatoid Arthritis in Korea for 11 Years (2006–2017) |
| title_short | Incidence Trends of Rheumatoid Arthritis in Korea for 11 Years (2006–2017) |
| title_sort | incidence trends of rheumatoid arthritis in korea for 11 years 2006 2017 |
| topic | rheumatoid arthritis incidence autoimmune disease |
| url | https://www.mdpi.com/2039-7283/14/6/193 |
| work_keys_str_mv | AT hannalee incidencetrendsofrheumatoidarthritisinkoreafor11years20062017 AT sangillee incidencetrendsofrheumatoidarthritisinkoreafor11years20062017 AT hyunjinlim incidencetrendsofrheumatoidarthritisinkoreafor11years20062017 AT hyunokkim incidencetrendsofrheumatoidarthritisinkoreafor11years20062017 AT rockbumkim incidencetrendsofrheumatoidarthritisinkoreafor11years20062017 AT yunhongcheon incidencetrendsofrheumatoidarthritisinkoreafor11years20062017 |