Atypical course of Parkinson’s disease with clinical manifestations of Huntington’s disease in a patient with an allele of 27 CAG repeats in the HTT gene

Atypical course of Parkinson’s disease with clinical manifestations of Huntington’s disease in a patient with an allele of 27 CAG repeats in the HTT gene

Huntington’s disease (HD) is an autosomal dominant progressive neurodegenerative disease. Its molecular cause is a cytosine-adenine-guanine (CAG) trinucleotide repeat dynamic expansion in the huntingtin (HTT) gene. Alleles with 36–39 CAG-repeats are incompletely penetrant, as individuals might devel...

Full description

Saved in:
Bibliographic Details
Main Authors: M. A. Nikitina, E. Yu. Bragina, M. S. Nazarenko, N. G. Zhukova, D. E. Gomboeva, K. F. Nurzhanova, N. V. Tsentr, V. M. Alifirova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2021-01-01
Series:Бюллетень сибирской медицины
Subjects:
parkinsonism
parkinson’s disease
motor disorders
huntington’s disease
differential diagnosis
expansion of cag-repeats
htt
neurodegenerative diseases
genetics
Online Access:https://bulletin.ssmu.ru/jour/article/view/4173
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items