Heterogeneous treatment effects of stress ulcer prophylaxis among ICU patients at risk for gastrointestinal bleeding

Heterogeneous treatment effects of stress ulcer prophylaxis among ICU patients at risk for gastrointestinal bleeding

Abstract Background While randomized clinical trials of stress ulcer prophylaxis (SUP) have generally shown no overall benefit, subgroup analyses suggest the benefit or harm of SUP in specific patients, indicating heterogeneity of treatment effects (HTE). Understanding HTE is crucial for tailoring S...

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Bibliographic Details
Main Authors: Yongpeng Xie, Yao Yan, Qixiang Hong, Hui Zheng, Lijuan Cao, Xiaoming Li, Songqiao Liu, Hui Chen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Medicine
Subjects:
Stress ulcer prophylaxis
Heterogeneity of treatment effects
Intensive care unit
Gastrointestinal bleeding
Online Access:https://doi.org/10.1186/s12916-025-04038-6
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