In vitro activity of essential oils against Pseudomonas aeruginosa isolated from infected hip implants

Introduction: Essential oils have been used since ancient times and are known for their anti-inflammatory, anti-depressive, antiseptic, antifungal and antimicrobial properties. Methodology: in this study the antimicrobial activity of two essential oils from Melaleuca alternifolia and Thymus vulg...

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Main Authors: Veronica Amorese, Matthew Donadu, Donatella Usai, Angelino Sanna, Fabio Milia, Francesco Pisanu, Paola Molicotti, Stefania Zanetti, Carlo Doria
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2018-11-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/10988
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author Veronica Amorese
Matthew Donadu
Donatella Usai
Angelino Sanna
Fabio Milia
Francesco Pisanu
Paola Molicotti
Stefania Zanetti
Carlo Doria
author_facet Veronica Amorese
Matthew Donadu
Donatella Usai
Angelino Sanna
Fabio Milia
Francesco Pisanu
Paola Molicotti
Stefania Zanetti
Carlo Doria
author_sort Veronica Amorese
collection DOAJ
description Introduction: Essential oils have been used since ancient times and are known for their anti-inflammatory, anti-depressive, antiseptic, antifungal and antimicrobial properties. Methodology: in this study the antimicrobial activity of two essential oils from Melaleuca alternifolia and Thymus vulgaris–red thyme geraniol was tested against 16 multidrug-resistant P. aeruginosa strains from infected hip implants as well as the “in vitro” cytotoxic activity on normal human Wong-Kilbourne derivative (WKD) cells. Results: Thymus vulgaris–red thyme geraniol showed lower antimicrobial activity when compared to Melaleuca alternifolia. All tested oils were cytotoxic at concentrations lower than 0.12%. Conclusion: Increase in drug resistance and lack of new antibiotics may encourage the development of natural treatments together with higher concern on environmental issues and natural lifestyle.
format Article
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institution OA Journals
issn 1972-2680
language English
publishDate 2018-11-01
publisher The Journal of Infection in Developing Countries
record_format Article
series Journal of Infection in Developing Countries
spelling doaj-art-e88e6ed19d2a4f2281a6fa5be34ec5952025-08-20T02:27:23ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802018-11-01121110.3855/jidc.10988In vitro activity of essential oils against Pseudomonas aeruginosa isolated from infected hip implantsVeronica Amorese0Matthew Donadu1Donatella Usai2Angelino Sanna3Fabio Milia4Francesco Pisanu5Paola Molicotti6Stefania Zanetti7Carlo Doria8University of Sassari, Sassari, ItalyUniversity of Sassari, Sassari, ItalyUniversity of Sassari, Sassari, ItalyUniversity of Sassari, Sassari, ItalyUniversity of Sassari, Sassari, ItalyUniversity of Sassari, Sassari, ItalyUniversity of Sassari, Sassari, ItalyUniversity of Sassari, Sassari, ItalyUniversity of Sassari, Sassari, Italy Introduction: Essential oils have been used since ancient times and are known for their anti-inflammatory, anti-depressive, antiseptic, antifungal and antimicrobial properties. Methodology: in this study the antimicrobial activity of two essential oils from Melaleuca alternifolia and Thymus vulgaris–red thyme geraniol was tested against 16 multidrug-resistant P. aeruginosa strains from infected hip implants as well as the “in vitro” cytotoxic activity on normal human Wong-Kilbourne derivative (WKD) cells. Results: Thymus vulgaris–red thyme geraniol showed lower antimicrobial activity when compared to Melaleuca alternifolia. All tested oils were cytotoxic at concentrations lower than 0.12%. Conclusion: Increase in drug resistance and lack of new antibiotics may encourage the development of natural treatments together with higher concern on environmental issues and natural lifestyle. https://jidc.org/index.php/journal/article/view/10988Antimicrobialsbiopharmaceuticalship implantsinfectionPseudomonas spp
spellingShingle Veronica Amorese
Matthew Donadu
Donatella Usai
Angelino Sanna
Fabio Milia
Francesco Pisanu
Paola Molicotti
Stefania Zanetti
Carlo Doria
In vitro activity of essential oils against Pseudomonas aeruginosa isolated from infected hip implants
Journal of Infection in Developing Countries
Antimicrobials
biopharmaceuticals
hip implants
infection
Pseudomonas spp
title In vitro activity of essential oils against Pseudomonas aeruginosa isolated from infected hip implants
title_full In vitro activity of essential oils against Pseudomonas aeruginosa isolated from infected hip implants
title_fullStr In vitro activity of essential oils against Pseudomonas aeruginosa isolated from infected hip implants
title_full_unstemmed In vitro activity of essential oils against Pseudomonas aeruginosa isolated from infected hip implants
title_short In vitro activity of essential oils against Pseudomonas aeruginosa isolated from infected hip implants
title_sort in vitro activity of essential oils against pseudomonas aeruginosa isolated from infected hip implants
topic Antimicrobials
biopharmaceuticals
hip implants
infection
Pseudomonas spp
url https://jidc.org/index.php/journal/article/view/10988
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