Evaluation of Southern African wild edible plants for potential herb-drug interactions through ex vivo p-glycoprotein and in vitro cytochrome P450 3A4 inhibitory effects
Background: Wild edible plants (WEPs) including herbs provide staple foods as well as income for local communities on the African continent. However, these commonly used plant materials interact with orthodox or conventional drugs through both p-glycoprotein (P-gp) and cytochrome P450 enzymes inhibi...
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Main Authors: | P.S. Kheoane, K.C. Mokhetho, S. Mokhele, K.C. Mbara, C.M. Leonard, T.H. Gadaga, C. Tarirai |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
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Series: | Phytomedicine Plus |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667031324001556 |
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