Functional and Structural Consequences of Single-Nucleotide Polymorphisms in the NPM1 Gene Associated with Acute Myeloid Leukemia: Insights from a Comprehensive Bioinformatics Approach
NPM1 is a protein-coding gene that encodes the nucleophosmin 1 (NPM1) protein. The NPM1 protein exhibits dynamic shuttling between the nucleus and cytoplasm and is involved in various cellular processes, such as centrosome duplication, protein chaperoning, and DNA repair. Mutations of the NPM1 gene...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Association for the Advancement of Science (AAAS)
2025-01-01
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| Series: | Journal of Bio-X Research |
| Online Access: | https://spj.science.org/doi/10.34133/jbioxresearch.0038 |
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