Results of the experimental study of the antimicrobial activity of therapeutic waters from various wells managed by the federation of trade unions of Uzbekistan
Introduction. Currently, in addition to the traditional use of mineral waters (MW) for the treatment of gastrointestinal tract and renal diseases, they are also used to correct metabolic disorders, normalize lipid and carbohydrate metabolism. However, many of its properties remain poorly studied, an...
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Ministry of Health of the Russian Federation. National Medical Research Center of Rehabilitation and Balneology
2024-11-01
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| author | Shuhnaza T. Iskandarova Zokhid A. Abdurakhimov Dilnoza M. Musaeva |
| author_facet | Shuhnaza T. Iskandarova Zokhid A. Abdurakhimov Dilnoza M. Musaeva |
| author_sort | Shuhnaza T. Iskandarova |
| collection | DOAJ |
| description | Introduction. Currently, in addition to the traditional use of mineral waters (MW) for the treatment of gastrointestinal tract and renal diseases, they are also used to correct metabolic disorders, normalize lipid and carbohydrate metabolism. However, many of its properties remain poorly studied, and there is a very limited number of works in the scientific literature concerning the analysis of their antibacterial action.
Aim. Study of sensitivity of common microorganisms to the action of some MW.
Materials and methods. The following test samples from different wells (DW) served as materials for determining the antimicrobial activity of mineral waters: Sample 1. Sodium bicarbonate weakly alkaline mineral water from SW No. 7 (Chinobod Sanatorium, Tashkent); Sample 2. Radon mineral water mineral water from SW No. 2 (Abu Ali ibn Sino Sanatorium, Samarkand Region); Sample 3. Iodine-bromine mineral water from SW No. 4 (Chartak Sanatorium, Namangan Region); Sample 4. Sulfate-sulfur mineral water from SW No. 14 (Chimen Sanatorium, Fergana Region); Sample 5. Concentrated iodine-bromine brine from SCW No. 2 (Chartak Sanatorium, Namangan Region).
Results and discussion. Sample No. 5 (concentrated brine) showed antimicrobial activity against Staphylococcus aureus and Pseudomonas aeruginosa, the diameter of the growth inhibition zone was 22 ± 0.26 and 18 ± 0.35 mm, respectively. Also, sample No. 4 (Sanatorium Chimen DW No = 14, sulfate-sulfur mineral water) showed antimicrobial activity against Staphylococcus aureus, the diameter of the growth inhibition zone was 16 ± 0.11 mm. The samples did not show antimicrobial activity against the other test cultures. The antimicrobial action of water samples was determined by the agar diffusion method against some types of opportunistic bacteria: Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis and the yeast fungus Candida albicans. All microorganism cultures were obtained from the collection of the Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan. The determination was achieved through the use of the agar diffusion method on a dense nutrient medium.
Conclusion. It was found that sample No. 5 concentrated brine «Iodine-shifo» from the Chartak Sanatorium showed antimicrobial activity against Staphylococcus aureus and Pseudomonas aeruginosa, i. e. Staphylococcus aureus and Pseudomonas aeruginosa, the diameter of the growth inhibition zone was 22 ± 0.26 and 18 ± 0.35 mm, respectively. Also, sample No. 4 sulfate-sulfur mineral water from the Chimen Sanatorium showed antimicrobial activity against Staphylococcus aureus, the diameter of the growth inhibition zone was 16 ± 0.11 mm. The samples did not show antimicrobial activity against the other test cultures. |
| format | Article |
| id | doaj-art-e87ed83777f2468888edaf0f4cc5961e |
| institution | OA Journals |
| issn | 2078-1962 2713-2625 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Ministry of Health of the Russian Federation. National Medical Research Center of Rehabilitation and Balneology |
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| series | Вестник восстановительной медицины |
| spelling | doaj-art-e87ed83777f2468888edaf0f4cc5961e2025-08-20T02:33:47ZengMinistry of Health of the Russian Federation. National Medical Research Center of Rehabilitation and BalneologyВестник восстановительной медицины2078-19622713-26252024-11-01235798610.38025/2078-1962-2024-23-5-79-861433Results of the experimental study of the antimicrobial activity of therapeutic waters from various wells managed by the federation of trade unions of UzbekistanShuhnaza T. Iskandarova0https://orcid.org/0000-0002-9378-7492Zokhid A. Abdurakhimov1https://orcid.org/0009-0000-2257-3254Dilnoza M. Musaeva2Tashkent Pediatric Medical InstituteTashkent Pediatric Medical Institute«Chinabad plaza» Sanatorium of the Federation of Trade Unions of UzbekistanIntroduction. Currently, in addition to the traditional use of mineral waters (MW) for the treatment of gastrointestinal tract and renal diseases, they are also used to correct metabolic disorders, normalize lipid and carbohydrate metabolism. However, many of its properties remain poorly studied, and there is a very limited number of works in the scientific literature concerning the analysis of their antibacterial action. Aim. Study of sensitivity of common microorganisms to the action of some MW. Materials and methods. The following test samples from different wells (DW) served as materials for determining the antimicrobial activity of mineral waters: Sample 1. Sodium bicarbonate weakly alkaline mineral water from SW No. 7 (Chinobod Sanatorium, Tashkent); Sample 2. Radon mineral water mineral water from SW No. 2 (Abu Ali ibn Sino Sanatorium, Samarkand Region); Sample 3. Iodine-bromine mineral water from SW No. 4 (Chartak Sanatorium, Namangan Region); Sample 4. Sulfate-sulfur mineral water from SW No. 14 (Chimen Sanatorium, Fergana Region); Sample 5. Concentrated iodine-bromine brine from SCW No. 2 (Chartak Sanatorium, Namangan Region). Results and discussion. Sample No. 5 (concentrated brine) showed antimicrobial activity against Staphylococcus aureus and Pseudomonas aeruginosa, the diameter of the growth inhibition zone was 22 ± 0.26 and 18 ± 0.35 mm, respectively. Also, sample No. 4 (Sanatorium Chimen DW No = 14, sulfate-sulfur mineral water) showed antimicrobial activity against Staphylococcus aureus, the diameter of the growth inhibition zone was 16 ± 0.11 mm. The samples did not show antimicrobial activity against the other test cultures. The antimicrobial action of water samples was determined by the agar diffusion method against some types of opportunistic bacteria: Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis and the yeast fungus Candida albicans. All microorganism cultures were obtained from the collection of the Institute of Microbiology of the Academy of Sciences of the Republic of Uzbekistan. The determination was achieved through the use of the agar diffusion method on a dense nutrient medium. Conclusion. It was found that sample No. 5 concentrated brine «Iodine-shifo» from the Chartak Sanatorium showed antimicrobial activity against Staphylococcus aureus and Pseudomonas aeruginosa, i. e. Staphylococcus aureus and Pseudomonas aeruginosa, the diameter of the growth inhibition zone was 22 ± 0.26 and 18 ± 0.35 mm, respectively. Also, sample No. 4 sulfate-sulfur mineral water from the Chimen Sanatorium showed antimicrobial activity against Staphylococcus aureus, the diameter of the growth inhibition zone was 16 ± 0.11 mm. The samples did not show antimicrobial activity against the other test cultures.https://journals.eco-vector.com/2078-1962/article/viewFile/642156/157932uzbekistananti-bacterial agentsnutrientsgastrointestinal tractkidney diseaseslipidswater |
| spellingShingle | Shuhnaza T. Iskandarova Zokhid A. Abdurakhimov Dilnoza M. Musaeva Results of the experimental study of the antimicrobial activity of therapeutic waters from various wells managed by the federation of trade unions of Uzbekistan Вестник восстановительной медицины uzbekistan anti-bacterial agents nutrients gastrointestinal tract kidney diseases lipids water |
| title | Results of the experimental study of the antimicrobial activity of therapeutic waters from various wells managed by the federation of trade unions of Uzbekistan |
| title_full | Results of the experimental study of the antimicrobial activity of therapeutic waters from various wells managed by the federation of trade unions of Uzbekistan |
| title_fullStr | Results of the experimental study of the antimicrobial activity of therapeutic waters from various wells managed by the federation of trade unions of Uzbekistan |
| title_full_unstemmed | Results of the experimental study of the antimicrobial activity of therapeutic waters from various wells managed by the federation of trade unions of Uzbekistan |
| title_short | Results of the experimental study of the antimicrobial activity of therapeutic waters from various wells managed by the federation of trade unions of Uzbekistan |
| title_sort | results of the experimental study of the antimicrobial activity of therapeutic waters from various wells managed by the federation of trade unions of uzbekistan |
| topic | uzbekistan anti-bacterial agents nutrients gastrointestinal tract kidney diseases lipids water |
| url | https://journals.eco-vector.com/2078-1962/article/viewFile/642156/157932 |
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