Blood Transfusion Recipients with Alloantibodies of Anti C, c, E, e and Anti D+C (?G): A Series of 11 Cases
The process whereby non ABO antibodies form after a Red Blood Cell (RBC) transfusion, pregnancy, or transplantation is known as alloimmunisation. The likelihood of developing alloimmunisation is influenced by factors such as transfusions, multiple pregnancies, underlying diseases, the cause of anaem...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2025-08-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/article_fulltext.asp?issn=0973-709x&year=2025&volume=19&issue=8&page=ER01&issn=0973-709x&id=21410 |
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| Summary: | The process whereby non ABO antibodies form after a Red Blood Cell (RBC) transfusion, pregnancy, or transplantation is known as alloimmunisation. The likelihood of developing alloimmunisation is influenced by factors such as transfusions, multiple pregnancies, underlying diseases, the cause of anaemia, and the recipient’s immune response to the non-self RBC antigens they encounter. Alloantibodies can complicate crossmatch testing, leading to delays in securing compatible blood. Therefore, for a patient with a history of detectable clinically significant antibodies, donor units selected for transfusion must be negative for the corresponding antigen(s). In this context, the authors present a series of 11 cases (7males ,4 females) transfusion recipients and their characteristics for being at risk of alloimmunisation. |
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| ISSN: | 2249-782X 0973-709X |