Neutrophils and Platelets as Key Players in the Pathogenesis of ANCA-Associated Vasculitis and Potential Sources of Disease Activity Biomarkers

Neutrophils and Platelets as Key Players in the Pathogenesis of ANCA-Associated Vasculitis and Potential Sources of Disease Activity Biomarkers

Anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) is a heterogeneous group of small-vessel vasculitides, characterized by the presence of antibodies binding to myeloperoxidase (MPO) and proteinase-3 (PR3) found in neutrophil granules. Apart from being the target of ANCA, neut...

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Bibliographic Details
Main Authors: Anna Drynda, Marcin Surmiak, Stanisława Bazan-Socha, Katarzyna Wawrzycka-Adamczyk, Mariusz Korkosz, Jacek Musiał, Krzysztof Wójcik
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Diagnostics
Subjects:
ANCA-associated vasculitis (AAV)
neutrophils
platelets
myeloperoxidase (MPO)
proteinase-3 (PR3)
neutrophil extracellular traps (NETs)
Online Access:https://www.mdpi.com/2075-4418/15/15/1905
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