Systemic inflammation in response to radiation drives the genesis of an immunosuppressed tumor microenvironment

The composition of the tumor immune microenvironment has become a major determinant of response to therapy, particularly immunotherapy. Clinically, a tumor microenvironment lacking lymphocytes, so-called ''cold'' tumors, are considered poor candidates for immune checkpoint inhibi...

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Bibliographic Details
Main Authors: Lin Ma, Jian-Hua Mao, Mary Helen Barcellos-Hoff
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Neoplasia: An International Journal for Oncology Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S1476558625000430
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