miR-107 modulates EMT progression of OSCC by targeting SNCG and inhibiting the ERK/NF-κB signaling pathways

miR-107 modulates EMT progression of OSCC by targeting SNCG and inhibiting the ERK/NF-κB signaling pathways

Abstract Background Oral squamous cell carcinoma (OSCC) is marked by aggressive metastasis and poor prognosis, with epithelial-mesenchymal transition (EMT) serving as a pivotal process in tumor metastasis. Consequently, identifying critical targets and elucidating the underlying mechanisms that driv...

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Bibliographic Details
Main Authors: Han Liu, Jun Zheng, Zuodong Ren, Kangyuan Shen, Yan Zeng
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Translational Medicine
Subjects:
Oral squamous cell carcinoma
miR-107
SNCG
Migration
Invasion
EMT
Online Access:https://doi.org/10.1186/s12967-025-06910-8
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