Exploring the gut microbiome and serum metabolome interplay in non-functioning pituitary neuroendocrine tumors

Exploring the gut microbiome and serum metabolome interplay in non-functioning pituitary neuroendocrine tumors

The gut microbiome has emerged as a potential factor in cancer pathogenesis, but its role in non-functioning pituitary neuroendocrine tumors (NF-PitNETs) remains unclear. This study aimed to elucidate gut microbiome and metabolomic alterations in NF-PitNETs by comparing microbial diversity, pathogen...

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Bibliographic Details
Main Authors: Jifang Liu, Zhang Ye, Yi Zhang, Wan Su, Jie Liu, Tianqi Chen, Yanan Shi, Lulu Liu, Jiao Lu, Zian Cai, Qing Zhong, Pei Wang, Jun Pu, Jinghua Liu, Yuchen Wei, Hui Pan, Huijuan Zhu, Kan Deng, Renzhi Wang, Lin Lu, Xiaomin Hu, Yong Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Microbiology
Subjects:
NF-PitNETs
gut microbiota
serum metabolomics
microbiome-metabolome interactions
tumor aggressiveness
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1541683/full
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