Short-term fasting early in life extends lifespan in a mite Amblydromalus limonicus (Acari: Phytoseiidae)

Abstract Dietary restriction is one of the most effective and reproducible dietary interventions known to regulate aging and increase the healthy lifespan in various model organisms, ranging from the unicellular yeast to worms, flies, rodents, and primates. This study examined the effects of short-t...

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Main Authors: Pei-Ying Peng, Zhi-Qiang Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-12152-x
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author Pei-Ying Peng
Zhi-Qiang Zhang
author_facet Pei-Ying Peng
Zhi-Qiang Zhang
author_sort Pei-Ying Peng
collection DOAJ
description Abstract Dietary restriction is one of the most effective and reproducible dietary interventions known to regulate aging and increase the healthy lifespan in various model organisms, ranging from the unicellular yeast to worms, flies, rodents, and primates. This study examined the effects of short-term fasting during early life (STFEL) on longevity in the phytoseiid predatory mite Amblydromalus limonicus, hypothesizing that STFEL—especially at the facultative feeding larval stage—would extend lifespan. Experimental mites were divided into a control group with no fasting and four treatment groups subjected to 1-day fasting at the start in different developmental stages: Larval (T1), protonymph (T2), deutonymph (T3), and adult (T4). Results demonstrate that STFEL could significantly extends lifespan, with the most pronounced effects observed when fasting occurred at the start of the larval stage compared to other periods. These findings highlight the adaptive role of facultative feeding larvae and provide a foundation for developing physiological enhancement strategies in biocontrol applications.
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spelling doaj-art-e861ec8010d74072b5d348bd4bca21cb2025-08-20T03:05:22ZengNature PortfolioScientific Reports2045-23222025-07-0115111010.1038/s41598-025-12152-xShort-term fasting early in life extends lifespan in a mite Amblydromalus limonicus (Acari: Phytoseiidae)Pei-Ying Peng0Zhi-Qiang Zhang1Institute of Microbiology, Qujing Medical CollegeManaaki Whenua Landcare Research Group, Bioeconomy Science InstituteAbstract Dietary restriction is one of the most effective and reproducible dietary interventions known to regulate aging and increase the healthy lifespan in various model organisms, ranging from the unicellular yeast to worms, flies, rodents, and primates. This study examined the effects of short-term fasting during early life (STFEL) on longevity in the phytoseiid predatory mite Amblydromalus limonicus, hypothesizing that STFEL—especially at the facultative feeding larval stage—would extend lifespan. Experimental mites were divided into a control group with no fasting and four treatment groups subjected to 1-day fasting at the start in different developmental stages: Larval (T1), protonymph (T2), deutonymph (T3), and adult (T4). Results demonstrate that STFEL could significantly extends lifespan, with the most pronounced effects observed when fasting occurred at the start of the larval stage compared to other periods. These findings highlight the adaptive role of facultative feeding larvae and provide a foundation for developing physiological enhancement strategies in biocontrol applications.https://doi.org/10.1038/s41598-025-12152-xCaloric restrictionIntermittent fastingAgingBiological controlLife duration
spellingShingle Pei-Ying Peng
Zhi-Qiang Zhang
Short-term fasting early in life extends lifespan in a mite Amblydromalus limonicus (Acari: Phytoseiidae)
Scientific Reports
Caloric restriction
Intermittent fasting
Aging
Biological control
Life duration
title Short-term fasting early in life extends lifespan in a mite Amblydromalus limonicus (Acari: Phytoseiidae)
title_full Short-term fasting early in life extends lifespan in a mite Amblydromalus limonicus (Acari: Phytoseiidae)
title_fullStr Short-term fasting early in life extends lifespan in a mite Amblydromalus limonicus (Acari: Phytoseiidae)
title_full_unstemmed Short-term fasting early in life extends lifespan in a mite Amblydromalus limonicus (Acari: Phytoseiidae)
title_short Short-term fasting early in life extends lifespan in a mite Amblydromalus limonicus (Acari: Phytoseiidae)
title_sort short term fasting early in life extends lifespan in a mite amblydromalus limonicus acari phytoseiidae
topic Caloric restriction
Intermittent fasting
Aging
Biological control
Life duration
url https://doi.org/10.1038/s41598-025-12152-x
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