Association between sleep duration and lung function among U.S. adults
Abstract Background Sleep’s impact on the human immune system and inflammatory responses makes it a potential risk factor for lung function impairment. However, the relationship between sleep duration and lung function impairment in middle-aged and young adults has been rarely investigated. Methods...
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2024-12-01
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| Online Access: | https://doi.org/10.1186/s12889-024-21024-4 |
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| author | Jingyang Li Xiaoqian Qian Guodong Ding Yongjun Zhang |
| author_facet | Jingyang Li Xiaoqian Qian Guodong Ding Yongjun Zhang |
| author_sort | Jingyang Li |
| collection | DOAJ |
| description | Abstract Background Sleep’s impact on the human immune system and inflammatory responses makes it a potential risk factor for lung function impairment. However, the relationship between sleep duration and lung function impairment in middle-aged and young adults has been rarely investigated. Methods A total of 9,284 aged 20–64 years were categorized into four groups according to sleep duration (≤ 6 h, 7 h, 8 h, and ≥ 9 h), with 7 h as the reference, by using the U.S. NHANES data, 2007–2012. Forced expiratory volume in the 1 s (FEV1), forced vital capacity (FVC), FEV1 to FVC (FEV1/FVC) ratio, peak expiratory flow (PEF), and forced expiratory flow at 25–75% (FEF25 − 75%) were measured by spirometry. Restrictive impairment was defined as baseline FVC < 80% predicted and obstructive impairment as FEV1/FVC < 0.70. Generalized linear regression and logistic regression were performed to estimate the associations between sleep duration and lung function. Results Compared with 7 h of sleep duration, shorter and longer sleep duration were associated with decreases in FEV1 (≤ 6 h: β=-0.010, 95% CI=-0.014 to -0.006; 8 h: β=-0.005, 95% CI=-0.009 to -0.001), FVC (≤ 6 h: β=-0.018, 95% CI=-0.014 to -0.007; 8 h: β=-0.005, 95% CI=-0.009 to -0.002), and PEF (≤ 6 h: β=-0.006, 95% CI=-0.010 to -0.002; 8 h: β=-0.007, 95% CI=-0.011 to -0.002; ≥ 9 h: β=-0.012, 95% CI=-0.020 to -0.004). Similarly, shorter (≤ 6 h: OR = 1.346, 95% CI = 1.065 to 1.700) and longer (≥ 9 h: OR = 1.827, 95% CI = 1.236 to 2.700) sleep duration were associated with increased risks of restrictive impairment. Moreover, the aforementioned associations were more pronounced among male participants. Conclusions Compared with 7 h of sleep duration, shorter and longer sleep duration were associated with impaired lung function among adults aged 20–64 years, and these associations were stronger among males. |
| format | Article |
| id | doaj-art-e85e536c649a477a97a67d7ce62b66da |
| institution | DOAJ |
| issn | 1471-2458 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj-art-e85e536c649a477a97a67d7ce62b66da2025-08-20T02:40:17ZengBMCBMC Public Health1471-24582024-12-0124111110.1186/s12889-024-21024-4Association between sleep duration and lung function among U.S. adultsJingyang Li0Xiaoqian Qian1Guodong Ding2Yongjun Zhang3Department of Pediatrics, Xinhua Hospital, Shanghai Jiao Tong University School of MedicineRenal Division, Department of Internal Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Pediatrics, Xinhua Hospital, Shanghai Jiao Tong University School of MedicineDepartment of Pediatrics, Xinhua Hospital, Shanghai Jiao Tong University School of MedicineAbstract Background Sleep’s impact on the human immune system and inflammatory responses makes it a potential risk factor for lung function impairment. However, the relationship between sleep duration and lung function impairment in middle-aged and young adults has been rarely investigated. Methods A total of 9,284 aged 20–64 years were categorized into four groups according to sleep duration (≤ 6 h, 7 h, 8 h, and ≥ 9 h), with 7 h as the reference, by using the U.S. NHANES data, 2007–2012. Forced expiratory volume in the 1 s (FEV1), forced vital capacity (FVC), FEV1 to FVC (FEV1/FVC) ratio, peak expiratory flow (PEF), and forced expiratory flow at 25–75% (FEF25 − 75%) were measured by spirometry. Restrictive impairment was defined as baseline FVC < 80% predicted and obstructive impairment as FEV1/FVC < 0.70. Generalized linear regression and logistic regression were performed to estimate the associations between sleep duration and lung function. Results Compared with 7 h of sleep duration, shorter and longer sleep duration were associated with decreases in FEV1 (≤ 6 h: β=-0.010, 95% CI=-0.014 to -0.006; 8 h: β=-0.005, 95% CI=-0.009 to -0.001), FVC (≤ 6 h: β=-0.018, 95% CI=-0.014 to -0.007; 8 h: β=-0.005, 95% CI=-0.009 to -0.002), and PEF (≤ 6 h: β=-0.006, 95% CI=-0.010 to -0.002; 8 h: β=-0.007, 95% CI=-0.011 to -0.002; ≥ 9 h: β=-0.012, 95% CI=-0.020 to -0.004). Similarly, shorter (≤ 6 h: OR = 1.346, 95% CI = 1.065 to 1.700) and longer (≥ 9 h: OR = 1.827, 95% CI = 1.236 to 2.700) sleep duration were associated with increased risks of restrictive impairment. Moreover, the aforementioned associations were more pronounced among male participants. Conclusions Compared with 7 h of sleep duration, shorter and longer sleep duration were associated with impaired lung function among adults aged 20–64 years, and these associations were stronger among males.https://doi.org/10.1186/s12889-024-21024-4FEV1FVCLung functionNHANESRestrictive impairmentSleep duration |
| spellingShingle | Jingyang Li Xiaoqian Qian Guodong Ding Yongjun Zhang Association between sleep duration and lung function among U.S. adults BMC Public Health FEV1 FVC Lung function NHANES Restrictive impairment Sleep duration |
| title | Association between sleep duration and lung function among U.S. adults |
| title_full | Association between sleep duration and lung function among U.S. adults |
| title_fullStr | Association between sleep duration and lung function among U.S. adults |
| title_full_unstemmed | Association between sleep duration and lung function among U.S. adults |
| title_short | Association between sleep duration and lung function among U.S. adults |
| title_sort | association between sleep duration and lung function among u s adults |
| topic | FEV1 FVC Lung function NHANES Restrictive impairment Sleep duration |
| url | https://doi.org/10.1186/s12889-024-21024-4 |
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