KDM3A and KDM3B regulate alternative splicing in mouse pluripotent stem cells

Summary: Histone modifying enzymes are crucial in preserving cell identity by establishing a conducive chromatin environment for lineage specific transcription factor activity. Mouse pluripotent embryonic stem cells (mESCs) show lower levels of gene repression associated with histone modifications,...

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Bibliographic Details
Main Authors: Caleb M. Dillingham, Harshini Cormaty, Ellen C. Morgan, Andrew I. Tak, Dakarai E. Esgdaille, Paul L. Boutz, Rupa Sridharan
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225008739
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