Multi-Omics Analysis of the Immune Effect of the Engineered Exosome Drug Delivery System in Inducing Macrophage Apoptosis

Multi-Omics Analysis of the Immune Effect of the Engineered Exosome Drug Delivery System in Inducing Macrophage Apoptosis

<b>Background:</b> In this study, exosomes were engineered with anti-CD47 antibody and loaded with rifapentine to improve their ability to target macrophages for drug delivery. <b>Methods:</b> Exosomes from RAW264.7 cell supernatant were extracted by differential centrifugati...

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Bibliographic Details
Main Authors: Wei Xiang, Zhoujun Zhu, Qisong Shang, Parhat Yasin, Yuanyuan Wu, Xinghua Song
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceutics
Subjects:
engineered exosomes
rifapentine
macrophage
transcriptome sequencing
proteomics
Online Access:https://www.mdpi.com/1999-4923/17/4/494
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