Potassium Dichromate Detection: Carbon Quantum Dot-based Fluorescent “Turn-Off” Nanoprobe Design
The occurrence of potassium dichromate in food poses serious health risks, including cancer and skin-related issues. Conventional sensing methods, known for their poor sensitivity, low selectivity, and high costs, highlight the need for improved detection methods. This study addresses this gap by ex...
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Tsinghua University Press
2025-03-01
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| Series: | Nano Biomedicine and Engineering |
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| Online Access: | https://www.sciopen.com/article/10.26599/NBE.2024.9290069 |
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| author | Priti Sharma Sopan Nangare Rahul Tade Pravin Patil Sanjkumar Bari Dipak Patil |
| author_facet | Priti Sharma Sopan Nangare Rahul Tade Pravin Patil Sanjkumar Bari Dipak Patil |
| author_sort | Priti Sharma |
| collection | DOAJ |
| description | The occurrence of potassium dichromate in food poses serious health risks, including cancer and skin-related issues. Conventional sensing methods, known for their poor sensitivity, low selectivity, and high costs, highlight the need for improved detection methods. This study addresses this gap by exploring the use of carbon quantum dots (CQDs) synthesized from Tamarindus indica leaves through an eco-friendly hydrothermal approach for the detection of potassium dichromate. Briefly, the synthesized CQDs underwent spectroscopic characterizations. Following this, the CQDs-based sensor was assessed for key analytical parameters such as sensitivity, selectivity, and the analysis of spiked milk samples to detect potassium dichromate. As a result, analyses of particle size and zeta potential confirmed the formation of stable, nanosized CQDs. The introduction of potassium dichromate led to the quenching of CQDs’ fluorescence, likely attributed to mechanisms such as the inner filter effect (IFE) and fluorescence resonance energy transfer (FRET). The established linearity range and limit of detection were determined to be 50–500 and 148 μmol/L, respectively. Confirmation of the sensor’s practicality was obtained through the analysis of spiked samples, suggesting that CQDs could potentially serve as a viable alternative for detecting potassium dichromate in milk samples in the future. |
| format | Article |
| id | doaj-art-e838a199d6ab47bc9bc6f3001cbacbaa |
| institution | Kabale University |
| issn | 2097-3837 2150-5578 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Tsinghua University Press |
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| series | Nano Biomedicine and Engineering |
| spelling | doaj-art-e838a199d6ab47bc9bc6f3001cbacbaa2025-08-20T03:40:17ZengTsinghua University PressNano Biomedicine and Engineering2097-38372150-55782025-03-0117115116010.26599/NBE.2024.9290069Potassium Dichromate Detection: Carbon Quantum Dot-based Fluorescent “Turn-Off” Nanoprobe DesignPriti Sharma0Sopan Nangare1Rahul Tade2Pravin Patil3Sanjkumar Bari4Dipak Patil5Department of Pharmaceutical Chemistry and Quality Assurance, H. R. Patel Institute of Pharmaceutical Education and Research, Shirpur 425405, Dhule (MS), IndiaDepartment of Pharmaceutical Chemistry and Quality Assurance, H. R. Patel Institute of Pharmaceutical Education and Research, Shirpur 425405, Dhule (MS), IndiaDepartment of Pharmaceutical Chemistry and Quality Assurance, H. R. Patel Institute of Pharmaceutical Education and Research, Shirpur 425405, Dhule (MS), IndiaDepartment of Pharmaceutical Chemistry and Quality Assurance, H. R. Patel Institute of Pharmaceutical Education and Research, Shirpur 425405, Dhule (MS), IndiaDepartment of Pharmaceutical Chemistry and Quality Assurance, H. R. Patel Institute of Pharmaceutical Education and Research, Shirpur 425405, Dhule (MS), IndiaDepartment of Pharmaceutical Chemistry, K. K. Wagh College of Pharmacy, Hirabai Haridas Vidyanagari, Amrutdham, Panchavati, Nashik 422 003, Nashik (MS), IndiaThe occurrence of potassium dichromate in food poses serious health risks, including cancer and skin-related issues. Conventional sensing methods, known for their poor sensitivity, low selectivity, and high costs, highlight the need for improved detection methods. This study addresses this gap by exploring the use of carbon quantum dots (CQDs) synthesized from Tamarindus indica leaves through an eco-friendly hydrothermal approach for the detection of potassium dichromate. Briefly, the synthesized CQDs underwent spectroscopic characterizations. Following this, the CQDs-based sensor was assessed for key analytical parameters such as sensitivity, selectivity, and the analysis of spiked milk samples to detect potassium dichromate. As a result, analyses of particle size and zeta potential confirmed the formation of stable, nanosized CQDs. The introduction of potassium dichromate led to the quenching of CQDs’ fluorescence, likely attributed to mechanisms such as the inner filter effect (IFE) and fluorescence resonance energy transfer (FRET). The established linearity range and limit of detection were determined to be 50–500 and 148 μmol/L, respectively. Confirmation of the sensor’s practicality was obtained through the analysis of spiked samples, suggesting that CQDs could potentially serve as a viable alternative for detecting potassium dichromate in milk samples in the future.https://www.sciopen.com/article/10.26599/NBE.2024.9290069carbon quantum dotspotassium dichromatefluorescencebiomedical sensornanoprobe |
| spellingShingle | Priti Sharma Sopan Nangare Rahul Tade Pravin Patil Sanjkumar Bari Dipak Patil Potassium Dichromate Detection: Carbon Quantum Dot-based Fluorescent “Turn-Off” Nanoprobe Design Nano Biomedicine and Engineering carbon quantum dots potassium dichromate fluorescence biomedical sensor nanoprobe |
| title | Potassium Dichromate Detection: Carbon Quantum Dot-based Fluorescent “Turn-Off” Nanoprobe Design |
| title_full | Potassium Dichromate Detection: Carbon Quantum Dot-based Fluorescent “Turn-Off” Nanoprobe Design |
| title_fullStr | Potassium Dichromate Detection: Carbon Quantum Dot-based Fluorescent “Turn-Off” Nanoprobe Design |
| title_full_unstemmed | Potassium Dichromate Detection: Carbon Quantum Dot-based Fluorescent “Turn-Off” Nanoprobe Design |
| title_short | Potassium Dichromate Detection: Carbon Quantum Dot-based Fluorescent “Turn-Off” Nanoprobe Design |
| title_sort | potassium dichromate detection carbon quantum dot based fluorescent turn off nanoprobe design |
| topic | carbon quantum dots potassium dichromate fluorescence biomedical sensor nanoprobe |
| url | https://www.sciopen.com/article/10.26599/NBE.2024.9290069 |
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