Mechanism of action and selection of endoscopic bariatric therapies for treatment of obesity
Endoscopic bariatric therapies (EBTs) are minimally invasive and safe procedures with favorable weight loss outcomes in obesity treatment. We aimed to present the weight loss mechanism of action of EBTs and an individualized selection method for patients with obesity. We searched PubMed, Medline, Sc...
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| Format: | Article |
| Language: | English |
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Korean Society of Gastrointestinal Endoscopy
2024-11-01
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| Series: | Clinical Endoscopy |
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| Online Access: | http://www.e-ce.org/upload/pdf/ce-2024-005.pdf |
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| author | Wissam Ghusn Gerardo Calderon Barham K. Abu Dayyeh Andres Acosta |
| author_facet | Wissam Ghusn Gerardo Calderon Barham K. Abu Dayyeh Andres Acosta |
| author_sort | Wissam Ghusn |
| collection | DOAJ |
| description | Endoscopic bariatric therapies (EBTs) are minimally invasive and safe procedures with favorable weight loss outcomes in obesity treatment. We aimed to present the weight loss mechanism of action of EBTs and an individualized selection method for patients with obesity. We searched PubMed, Medline, Scopus, Embase, and Google Scholar databases for studies on the topic from databases inception to July 1, 2023, written in English. We focused on EBTs potential mechanism of action to induce weight loss. We also present an expert opinion on a novel selection of EBTs based on their mechanism of action. EBTs can result in weight loss through variable mechanisms of action. They can induce earlier satiation, delay gastric emptying, restrict the accommodative response of the stomach, decrease caloric absorption, and alter the secretion of gastrointestinal hormones. Selecting EBTs may be guided through their mechanism of action by which patients with abnormal satiation may benefit more from tissue apposition devices and aspiration therapy while patients with fast gastric emptying may be better candidates for intragastric devices, endoscopic anastomosis devices, and duodenal mucosal resurfacing. Consequently, the selection of EBTs should be guided by the mechanism of action which is specific to each type of therapy. |
| format | Article |
| id | doaj-art-e8344c6ded544354bfcbe575bfb3917f |
| institution | OA Journals |
| issn | 2234-2400 2234-2443 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Korean Society of Gastrointestinal Endoscopy |
| record_format | Article |
| series | Clinical Endoscopy |
| spelling | doaj-art-e8344c6ded544354bfcbe575bfb3917f2025-08-20T02:38:49ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432024-11-0157670171010.5946/ce.2024.0057886Mechanism of action and selection of endoscopic bariatric therapies for treatment of obesityWissam Ghusn0Gerardo Calderon1Barham K. Abu Dayyeh2Andres Acosta3 Precision Medicine for Obesity Program, Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, MN, USA Precision Medicine for Obesity Program, Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, MN, USA Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA Precision Medicine for Obesity Program, Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, MN, USAEndoscopic bariatric therapies (EBTs) are minimally invasive and safe procedures with favorable weight loss outcomes in obesity treatment. We aimed to present the weight loss mechanism of action of EBTs and an individualized selection method for patients with obesity. We searched PubMed, Medline, Scopus, Embase, and Google Scholar databases for studies on the topic from databases inception to July 1, 2023, written in English. We focused on EBTs potential mechanism of action to induce weight loss. We also present an expert opinion on a novel selection of EBTs based on their mechanism of action. EBTs can result in weight loss through variable mechanisms of action. They can induce earlier satiation, delay gastric emptying, restrict the accommodative response of the stomach, decrease caloric absorption, and alter the secretion of gastrointestinal hormones. Selecting EBTs may be guided through their mechanism of action by which patients with abnormal satiation may benefit more from tissue apposition devices and aspiration therapy while patients with fast gastric emptying may be better candidates for intragastric devices, endoscopic anastomosis devices, and duodenal mucosal resurfacing. Consequently, the selection of EBTs should be guided by the mechanism of action which is specific to each type of therapy.http://www.e-ce.org/upload/pdf/ce-2024-005.pdfbariatric surgical proceduresobesityweight loss |
| spellingShingle | Wissam Ghusn Gerardo Calderon Barham K. Abu Dayyeh Andres Acosta Mechanism of action and selection of endoscopic bariatric therapies for treatment of obesity Clinical Endoscopy bariatric surgical procedures obesity weight loss |
| title | Mechanism of action and selection of endoscopic bariatric therapies for treatment of obesity |
| title_full | Mechanism of action and selection of endoscopic bariatric therapies for treatment of obesity |
| title_fullStr | Mechanism of action and selection of endoscopic bariatric therapies for treatment of obesity |
| title_full_unstemmed | Mechanism of action and selection of endoscopic bariatric therapies for treatment of obesity |
| title_short | Mechanism of action and selection of endoscopic bariatric therapies for treatment of obesity |
| title_sort | mechanism of action and selection of endoscopic bariatric therapies for treatment of obesity |
| topic | bariatric surgical procedures obesity weight loss |
| url | http://www.e-ce.org/upload/pdf/ce-2024-005.pdf |
| work_keys_str_mv | AT wissamghusn mechanismofactionandselectionofendoscopicbariatrictherapiesfortreatmentofobesity AT gerardocalderon mechanismofactionandselectionofendoscopicbariatrictherapiesfortreatmentofobesity AT barhamkabudayyeh mechanismofactionandselectionofendoscopicbariatrictherapiesfortreatmentofobesity AT andresacosta mechanismofactionandselectionofendoscopicbariatrictherapiesfortreatmentofobesity |