Effects of intra-dentate gyrus microinjection of myokine irisin on long-term potentiation in male rats

Effects of intra-dentate gyrus microinjection of myokine irisin on long-term potentiation in male rats

ABSTRACT Induction of long-term potentiation (LTP) increases the storage capacity of synapses in the hippocampal dentate gyrus (DG). Irisin is a myokine generated from FNDC5 (a gene precursor) during exercise. Although intra-cornu ammonis 1 administration of irisin fortifies LTP in mice with Alzheim...

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Bibliographic Details
Main Authors: Saeed Mohammadi, Shahrbanoo Oryan, Alireza Komaki, Akram Eidi, Mohammad Zarei
Format: Article
Language:English
Published: Thieme Revinter Publicações 2020-01-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Dentate gyrus
neuronal plasticity
long-term potentiation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2019001200881&tlng=en
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