The Artificial Intelligence-Driven Intelligent Laboratory for Organic Chemistry Synthesis

The deep integration and application of artificial intelligence to organic chemistry are propelling the development of organic chemistry synthesis laboratories toward an intelligent automated laboratory model characterized by “hardware + software + AI”. This paper systematically explores the overall...

Full description

Saved in:
Bibliographic Details
Main Authors: Tan Li, Weining Song, Nanjiang Chen, Qi Wang, Fangfang Gao, Yalan Xing, Shouluan Wu, Chao Song, Junjin Li, Yu Liu, Shenghua Li, Congying Wu, Zhenyu Zhang
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/15/13/7387
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849428978250547200
author Tan Li
Weining Song
Nanjiang Chen
Qi Wang
Fangfang Gao
Yalan Xing
Shouluan Wu
Chao Song
Junjin Li
Yu Liu
Shenghua Li
Congying Wu
Zhenyu Zhang
author_facet Tan Li
Weining Song
Nanjiang Chen
Qi Wang
Fangfang Gao
Yalan Xing
Shouluan Wu
Chao Song
Junjin Li
Yu Liu
Shenghua Li
Congying Wu
Zhenyu Zhang
author_sort Tan Li
collection DOAJ
description The deep integration and application of artificial intelligence to organic chemistry are propelling the development of organic chemistry synthesis laboratories toward an intelligent automated laboratory model characterized by “hardware + software + AI”. This paper systematically explores the overall framework of AI-driven intelligent laboratories for organic chemistry synthesis, achieving automation and flexibility through standardized experimental integration workstations and intelligent scheduling and collaborative management of experimental resources. By leveraging multimodal databases, the integration of large models, machine learning, and other AI technologies enables AI-driven closed-loop intelligent chemical experiments, including product prediction, molecular retrosynthetic planning, and synthesis reaction optimization. The paper proposes a cloud-based shared operational model for chemical laboratories, aiming to achieve socialized sharing and intelligent matching of experimental resources, thereby facilitating the accumulation and sharing of chemical experimental data to promote the intelligent development of organic chemistry synthesis experiments. Practical cases of building intelligent chemical laboratories are shared, providing paths for technology implementation in constructing the next generation of automated and intelligent chemical laboratories.
format Article
id doaj-art-e8260a79569f49d29b1069200dbd417f
institution Kabale University
issn 2076-3417
language English
publishDate 2025-06-01
publisher MDPI AG
record_format Article
series Applied Sciences
spelling doaj-art-e8260a79569f49d29b1069200dbd417f2025-08-20T03:28:29ZengMDPI AGApplied Sciences2076-34172025-06-011513738710.3390/app15137387The Artificial Intelligence-Driven Intelligent Laboratory for Organic Chemistry SynthesisTan Li0Weining Song1Nanjiang Chen2Qi Wang3Fangfang Gao4Yalan Xing5Shouluan Wu6Chao Song7Junjin Li8Yu Liu9Shenghua Li10Congying Wu11Zhenyu Zhang12School of Information Engineering, Nanchang University, Nanchang 330047, ChinaQuikTech Co., Ltd., Beijing 100088, ChinaSchool of Information Engineering, Nanchang University, Nanchang 330047, ChinaQuikTech Co., Ltd., Beijing 100088, ChinaSchool of Information Engineering, Nanchang University, Nanchang 330047, ChinaSchool of Materials Science and Engineering, Beihang University, Beijing 100191, ChinaQuikTech Co., Ltd., Beijing 100088, ChinaQuikTech Co., Ltd., Beijing 100088, ChinaSchool of Information Engineering, Nanchang University, Nanchang 330047, ChinaSchool of Information Engineering, Nanchang University, Nanchang 330047, ChinaSchool of Information Engineering, Nanchang University, Nanchang 330047, ChinaSchool of Information Engineering, Nanchang University, Nanchang 330047, ChinaSchool of Information Engineering, Nanchang University, Nanchang 330047, ChinaThe deep integration and application of artificial intelligence to organic chemistry are propelling the development of organic chemistry synthesis laboratories toward an intelligent automated laboratory model characterized by “hardware + software + AI”. This paper systematically explores the overall framework of AI-driven intelligent laboratories for organic chemistry synthesis, achieving automation and flexibility through standardized experimental integration workstations and intelligent scheduling and collaborative management of experimental resources. By leveraging multimodal databases, the integration of large models, machine learning, and other AI technologies enables AI-driven closed-loop intelligent chemical experiments, including product prediction, molecular retrosynthetic planning, and synthesis reaction optimization. The paper proposes a cloud-based shared operational model for chemical laboratories, aiming to achieve socialized sharing and intelligent matching of experimental resources, thereby facilitating the accumulation and sharing of chemical experimental data to promote the intelligent development of organic chemistry synthesis experiments. Practical cases of building intelligent chemical laboratories are shared, providing paths for technology implementation in constructing the next generation of automated and intelligent chemical laboratories.https://www.mdpi.com/2076-3417/15/13/7387organic chemistry synthesiscomputational chemistrylaboratory automationAI-driven intelligent chemical experimentcloud-based shared laboratory
spellingShingle Tan Li
Weining Song
Nanjiang Chen
Qi Wang
Fangfang Gao
Yalan Xing
Shouluan Wu
Chao Song
Junjin Li
Yu Liu
Shenghua Li
Congying Wu
Zhenyu Zhang
The Artificial Intelligence-Driven Intelligent Laboratory for Organic Chemistry Synthesis
Applied Sciences
organic chemistry synthesis
computational chemistry
laboratory automation
AI-driven intelligent chemical experiment
cloud-based shared laboratory
title The Artificial Intelligence-Driven Intelligent Laboratory for Organic Chemistry Synthesis
title_full The Artificial Intelligence-Driven Intelligent Laboratory for Organic Chemistry Synthesis
title_fullStr The Artificial Intelligence-Driven Intelligent Laboratory for Organic Chemistry Synthesis
title_full_unstemmed The Artificial Intelligence-Driven Intelligent Laboratory for Organic Chemistry Synthesis
title_short The Artificial Intelligence-Driven Intelligent Laboratory for Organic Chemistry Synthesis
title_sort artificial intelligence driven intelligent laboratory for organic chemistry synthesis
topic organic chemistry synthesis
computational chemistry
laboratory automation
AI-driven intelligent chemical experiment
cloud-based shared laboratory
url https://www.mdpi.com/2076-3417/15/13/7387
work_keys_str_mv AT tanli theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT weiningsong theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT nanjiangchen theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT qiwang theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT fangfanggao theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT yalanxing theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT shouluanwu theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT chaosong theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT junjinli theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT yuliu theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT shenghuali theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT congyingwu theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT zhenyuzhang theartificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT tanli artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT weiningsong artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT nanjiangchen artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT qiwang artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT fangfanggao artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT yalanxing artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT shouluanwu artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT chaosong artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT junjinli artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT yuliu artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT shenghuali artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT congyingwu artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis
AT zhenyuzhang artificialintelligencedrivenintelligentlaboratoryfororganicchemistrysynthesis