Cavernous Sinus Syndrome: A Unique Presentation of CD5+ Diffuse Large B-Cell Lymphoma

Abstract/Background Cavernous sinus syndrome (CSS) is characterized by signs and symptoms that result from the compression and/or disruption of function of the dural venous sinus. Causes of CSS include tumors, inflammation, infection, trauma, and cavernous sinus thrombosis. Although neoplasm is one...

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Main Authors: Louis Arens, Iyerus Tariku
Format: Article
Language:English
Published: American College of Physicians 2022-10-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2022.0249
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author Louis Arens
Iyerus Tariku
author_facet Louis Arens
Iyerus Tariku
author_sort Louis Arens
collection DOAJ
description Abstract/Background Cavernous sinus syndrome (CSS) is characterized by signs and symptoms that result from the compression and/or disruption of function of the dural venous sinus. Causes of CSS include tumors, inflammation, infection, trauma, and cavernous sinus thrombosis. Although neoplasm is one of the most common causes of CSS in a series of case analyses, CSS is an exceedingly rare initial presentation of lymphoma. Additionally, CSS is a potential cause of secondary headaches, particularly in elderly patients with concomitant neurologic deficits. Here, we discuss a patient case of de novo CD5+ diffuse large B-cell lymphoma that initially presented as CSS.
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series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-e81fae30f6e440fbb9fd11393ca788b52025-08-20T02:11:46ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642022-10-011810.7326/aimcc.2022.0249Cavernous Sinus Syndrome: A Unique Presentation of CD5+ Diffuse Large B-Cell LymphomaLouis Arens0Iyerus Tariku11University of Rochester Medical Center, Rochester, New York2Syracuse VA Medical Center, Syracuse, New YorkAbstract/Background Cavernous sinus syndrome (CSS) is characterized by signs and symptoms that result from the compression and/or disruption of function of the dural venous sinus. Causes of CSS include tumors, inflammation, infection, trauma, and cavernous sinus thrombosis. Although neoplasm is one of the most common causes of CSS in a series of case analyses, CSS is an exceedingly rare initial presentation of lymphoma. Additionally, CSS is a potential cause of secondary headaches, particularly in elderly patients with concomitant neurologic deficits. Here, we discuss a patient case of de novo CD5+ diffuse large B-cell lymphoma that initially presented as CSS.https://www.acpjournals.org/doi/10.7326/aimcc.2022.0249
spellingShingle Louis Arens
Iyerus Tariku
Cavernous Sinus Syndrome: A Unique Presentation of CD5+ Diffuse Large B-Cell Lymphoma
Annals of Internal Medicine: Clinical Cases
title Cavernous Sinus Syndrome: A Unique Presentation of CD5+ Diffuse Large B-Cell Lymphoma
title_full Cavernous Sinus Syndrome: A Unique Presentation of CD5+ Diffuse Large B-Cell Lymphoma
title_fullStr Cavernous Sinus Syndrome: A Unique Presentation of CD5+ Diffuse Large B-Cell Lymphoma
title_full_unstemmed Cavernous Sinus Syndrome: A Unique Presentation of CD5+ Diffuse Large B-Cell Lymphoma
title_short Cavernous Sinus Syndrome: A Unique Presentation of CD5+ Diffuse Large B-Cell Lymphoma
title_sort cavernous sinus syndrome a unique presentation of cd5 diffuse large b cell lymphoma
url https://www.acpjournals.org/doi/10.7326/aimcc.2022.0249
work_keys_str_mv AT louisarens cavernoussinussyndromeauniquepresentationofcd5diffuselargebcelllymphoma
AT iyerustariku cavernoussinussyndromeauniquepresentationofcd5diffuselargebcelllymphoma