Thermal performance and entropy generation analysis of hybrid nanofluids in a 3D cylindrical microtube: Implications for biomedical applications
This study presents a numerical analysis of transient natural convection, heat transfer, and entropy generation in a 3D cylindrical microtube containing a hybrid nanofluid with potential applications in biomedical engineering, such as targeted drug delivery and microfluidic heat exchangers. The anal...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-04-01
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| Series: | Case Studies in Thermal Engineering |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214157X25001339 |
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| author | Chenxu Duan Hassan Roshani Payam Jalili Bahram Jalili Irshad Ahmad Qasem M Al-Mdallal Pan Zhang |
| author_facet | Chenxu Duan Hassan Roshani Payam Jalili Bahram Jalili Irshad Ahmad Qasem M Al-Mdallal Pan Zhang |
| author_sort | Chenxu Duan |
| collection | DOAJ |
| description | This study presents a numerical analysis of transient natural convection, heat transfer, and entropy generation in a 3D cylindrical microtube containing a hybrid nanofluid with potential applications in biomedical engineering, such as targeted drug delivery and microfluidic heat exchangers. The analysis spans the time interval of 0 ≤ t ≤ 1.5 s and is based on dimensionless parameters, including Reynolds number, Richardson number, nanoparticle volume fraction, and Prandtl number. The hybrid nanofluid, composed of Al₂O₃ (5 %) and Cu (3 %) nanoparticles suspended in water, enhances flow and heat transfer characteristics, making it suitable for high-precision thermal management in micro-scale biomedical systems. Galerkin's finite element method is employed to solve the governing equations for flow behavior, temperature distribution, and entropy generation. Results indicate that increasing Reynolds and Richardson numbers intensifies flow and enhances velocity magnitudes, which is crucial for optimizing drug transport and thermal efficiency in microdevices. Additionally, entropy generation decreases with increasing Richardson number but rises with Reynolds number, while the average Nusselt number improves with both parameters, ensuring effective heat transfer performance in medical devices. |
| format | Article |
| id | doaj-art-e81cbbf2cd634c70855479c62e886fa3 |
| institution | OA Journals |
| issn | 2214-157X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Case Studies in Thermal Engineering |
| spelling | doaj-art-e81cbbf2cd634c70855479c62e886fa32025-08-20T01:57:40ZengElsevierCase Studies in Thermal Engineering2214-157X2025-04-016810587310.1016/j.csite.2025.105873Thermal performance and entropy generation analysis of hybrid nanofluids in a 3D cylindrical microtube: Implications for biomedical applicationsChenxu Duan0Hassan Roshani1Payam Jalili2Bahram Jalili3Irshad Ahmad4Qasem M Al-Mdallal5Pan Zhang6School of Mechanical Engineering, Sichuan University Jinjiang College, Meishan, Sichuan, 620860, ChinaDepartment of Mechanical Engineering, North Tehran Branch, Islamic Azad University, Tehran, IranDepartment of Mechanical Engineering, North Tehran Branch, Islamic Azad University, Tehran, IranDepartment of Mechanical Engineering, North Tehran Branch, Islamic Azad University, Tehran, IranDepartment of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi ArabiaDepartment of Mathematical Sciences, UAE University, Al-Ain, 15551, United Arab Emirates; Corresponding author.School of Mechanical Engineering, Sichuan University Jinjiang College, Meishan, Sichuan, 620860, ChinaThis study presents a numerical analysis of transient natural convection, heat transfer, and entropy generation in a 3D cylindrical microtube containing a hybrid nanofluid with potential applications in biomedical engineering, such as targeted drug delivery and microfluidic heat exchangers. The analysis spans the time interval of 0 ≤ t ≤ 1.5 s and is based on dimensionless parameters, including Reynolds number, Richardson number, nanoparticle volume fraction, and Prandtl number. The hybrid nanofluid, composed of Al₂O₃ (5 %) and Cu (3 %) nanoparticles suspended in water, enhances flow and heat transfer characteristics, making it suitable for high-precision thermal management in micro-scale biomedical systems. Galerkin's finite element method is employed to solve the governing equations for flow behavior, temperature distribution, and entropy generation. Results indicate that increasing Reynolds and Richardson numbers intensifies flow and enhances velocity magnitudes, which is crucial for optimizing drug transport and thermal efficiency in microdevices. Additionally, entropy generation decreases with increasing Richardson number but rises with Reynolds number, while the average Nusselt number improves with both parameters, ensuring effective heat transfer performance in medical devices.http://www.sciencedirect.com/science/article/pii/S2214157X25001339Transient convective heat transfer3D microtubeHybrid nanofluidEntropy generationAverage nusselt number |
| spellingShingle | Chenxu Duan Hassan Roshani Payam Jalili Bahram Jalili Irshad Ahmad Qasem M Al-Mdallal Pan Zhang Thermal performance and entropy generation analysis of hybrid nanofluids in a 3D cylindrical microtube: Implications for biomedical applications Case Studies in Thermal Engineering Transient convective heat transfer 3D microtube Hybrid nanofluid Entropy generation Average nusselt number |
| title | Thermal performance and entropy generation analysis of hybrid nanofluids in a 3D cylindrical microtube: Implications for biomedical applications |
| title_full | Thermal performance and entropy generation analysis of hybrid nanofluids in a 3D cylindrical microtube: Implications for biomedical applications |
| title_fullStr | Thermal performance and entropy generation analysis of hybrid nanofluids in a 3D cylindrical microtube: Implications for biomedical applications |
| title_full_unstemmed | Thermal performance and entropy generation analysis of hybrid nanofluids in a 3D cylindrical microtube: Implications for biomedical applications |
| title_short | Thermal performance and entropy generation analysis of hybrid nanofluids in a 3D cylindrical microtube: Implications for biomedical applications |
| title_sort | thermal performance and entropy generation analysis of hybrid nanofluids in a 3d cylindrical microtube implications for biomedical applications |
| topic | Transient convective heat transfer 3D microtube Hybrid nanofluid Entropy generation Average nusselt number |
| url | http://www.sciencedirect.com/science/article/pii/S2214157X25001339 |
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