Patiromer Acetate Induced Hypercalcemia: An Unreported Adverse Effect

Hyperkalemia, a potential life threating condition, is a commonly encountered problem in chronic kidney disease (CKD) patients. Patiromer acetate, a nonabsorbable cation exchange polymer, is a gastrointestinal agent for chronic therapy in patients with persistent hyperkalemia. Patiromer is generally...

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Main Authors: Shreeyukta Bhattarai, Stephen Pupillo, Gulshan Man Singh Dangol, Erdal Sarac
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2019/3507407
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author Shreeyukta Bhattarai
Stephen Pupillo
Gulshan Man Singh Dangol
Erdal Sarac
author_facet Shreeyukta Bhattarai
Stephen Pupillo
Gulshan Man Singh Dangol
Erdal Sarac
author_sort Shreeyukta Bhattarai
collection DOAJ
description Hyperkalemia, a potential life threating condition, is a commonly encountered problem in chronic kidney disease (CKD) patients. Patiromer acetate, a nonabsorbable cation exchange polymer, is a gastrointestinal agent for chronic therapy in patients with persistent hyperkalemia. Patiromer is generally well tolerated in patients; common side effects are gastrointestinal, such as diarrhea, constipation, flatulence, and vomiting. Hypercalcemia, although a theoretical possibility, has not been reported in any major clinical trials. We present a case of hypercalcemia associated with patiromer acetate used for treatment of hyperkalemia in a stage IV CKD patient. Clinicians should be aware of the possibility of hypercalcemia while taking patiromer.
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institution Kabale University
issn 2090-6641
2090-665X
language English
publishDate 2019-01-01
publisher Wiley
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series Case Reports in Nephrology
spelling doaj-art-e81c3b234aed4af4915cf8db2e4971262025-02-03T01:03:17ZengWileyCase Reports in Nephrology2090-66412090-665X2019-01-01201910.1155/2019/35074073507407Patiromer Acetate Induced Hypercalcemia: An Unreported Adverse EffectShreeyukta Bhattarai0Stephen Pupillo1Gulshan Man Singh Dangol2Erdal Sarac3Northeast Ohio Medical University, Department of Medicine, Rootstown, Ohio, USANortheast Ohio Medical University, Department of Medicine, Rootstown, Ohio, USANortheast Ohio Medical University, Department of Medicine, Rootstown, Ohio, USANortheast Ohio Medical University, Department of Medicine, Rootstown, Ohio, USAHyperkalemia, a potential life threating condition, is a commonly encountered problem in chronic kidney disease (CKD) patients. Patiromer acetate, a nonabsorbable cation exchange polymer, is a gastrointestinal agent for chronic therapy in patients with persistent hyperkalemia. Patiromer is generally well tolerated in patients; common side effects are gastrointestinal, such as diarrhea, constipation, flatulence, and vomiting. Hypercalcemia, although a theoretical possibility, has not been reported in any major clinical trials. We present a case of hypercalcemia associated with patiromer acetate used for treatment of hyperkalemia in a stage IV CKD patient. Clinicians should be aware of the possibility of hypercalcemia while taking patiromer.http://dx.doi.org/10.1155/2019/3507407
spellingShingle Shreeyukta Bhattarai
Stephen Pupillo
Gulshan Man Singh Dangol
Erdal Sarac
Patiromer Acetate Induced Hypercalcemia: An Unreported Adverse Effect
Case Reports in Nephrology
title Patiromer Acetate Induced Hypercalcemia: An Unreported Adverse Effect
title_full Patiromer Acetate Induced Hypercalcemia: An Unreported Adverse Effect
title_fullStr Patiromer Acetate Induced Hypercalcemia: An Unreported Adverse Effect
title_full_unstemmed Patiromer Acetate Induced Hypercalcemia: An Unreported Adverse Effect
title_short Patiromer Acetate Induced Hypercalcemia: An Unreported Adverse Effect
title_sort patiromer acetate induced hypercalcemia an unreported adverse effect
url http://dx.doi.org/10.1155/2019/3507407
work_keys_str_mv AT shreeyuktabhattarai patiromeracetateinducedhypercalcemiaanunreportedadverseeffect
AT stephenpupillo patiromeracetateinducedhypercalcemiaanunreportedadverseeffect
AT gulshanmansinghdangol patiromeracetateinducedhypercalcemiaanunreportedadverseeffect
AT erdalsarac patiromeracetateinducedhypercalcemiaanunreportedadverseeffect