Efficient recovery of procyanidins from grape residue by UAE-NADES and macroporous resin

This study developed a green, efficient method for extracting and purifying procyanidins (PC) from grape pomace (GP) using ultrasound-assisted extraction (UAE) with natural deep eutectic solvents (NADES). The process was optimized through single-factor experiments and Box-Behnken Design (BBD) respon...

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Main Authors: Changsen Wang, Yilin You, Weidong Huang, Jicheng Zhan
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Ultrasonics Sonochemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1350417725001798
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author Changsen Wang
Yilin You
Weidong Huang
Jicheng Zhan
author_facet Changsen Wang
Yilin You
Weidong Huang
Jicheng Zhan
author_sort Changsen Wang
collection DOAJ
description This study developed a green, efficient method for extracting and purifying procyanidins (PC) from grape pomace (GP) using ultrasound-assisted extraction (UAE) with natural deep eutectic solvents (NADES). The process was optimized through single-factor experiments and Box-Behnken Design (BBD) response surface methodology (RSM). Bioactive substances and antioxidant activities in the extracts were compared, and scanning electron microscope (SEM) analysis revealed the synergistic effects of UAE and NADES. A second-order kinetic model described the extraction process, and scale-up experiments confirmed feasibility. Macroporous resin adsorption and elution conditions were optimized for improved PC purification. The final product’s purity, ingredient, and NADES solvent recovery were evaluated. This study offers a green, efficient alternative for extracting high-value bioactive compounds from food by-products, with broad application potential.
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institution Kabale University
issn 1350-4177
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publishDate 2025-08-01
publisher Elsevier
record_format Article
series Ultrasonics Sonochemistry
spelling doaj-art-e8128fc3820049449217850968b597262025-08-20T03:45:31ZengElsevierUltrasonics Sonochemistry1350-41772025-08-0111910740010.1016/j.ultsonch.2025.107400Efficient recovery of procyanidins from grape residue by UAE-NADES and macroporous resinChangsen Wang0Yilin You1Weidong Huang2Jicheng Zhan3Beijing Key Laboratory of Viticulture and Enology, College of Food Science and Nutritional Engineering, China Agricultural University, Tsinghua East Road 17, Haidian District, Beijing 100083, ChinaBeijing Key Laboratory of Viticulture and Enology, College of Food Science and Nutritional Engineering, China Agricultural University, Tsinghua East Road 17, Haidian District, Beijing 100083, ChinaBeijing Key Laboratory of Viticulture and Enology, College of Food Science and Nutritional Engineering, China Agricultural University, Tsinghua East Road 17, Haidian District, Beijing 100083, ChinaCorresponding author.; Beijing Key Laboratory of Viticulture and Enology, College of Food Science and Nutritional Engineering, China Agricultural University, Tsinghua East Road 17, Haidian District, Beijing 100083, ChinaThis study developed a green, efficient method for extracting and purifying procyanidins (PC) from grape pomace (GP) using ultrasound-assisted extraction (UAE) with natural deep eutectic solvents (NADES). The process was optimized through single-factor experiments and Box-Behnken Design (BBD) response surface methodology (RSM). Bioactive substances and antioxidant activities in the extracts were compared, and scanning electron microscope (SEM) analysis revealed the synergistic effects of UAE and NADES. A second-order kinetic model described the extraction process, and scale-up experiments confirmed feasibility. Macroporous resin adsorption and elution conditions were optimized for improved PC purification. The final product’s purity, ingredient, and NADES solvent recovery were evaluated. This study offers a green, efficient alternative for extracting high-value bioactive compounds from food by-products, with broad application potential.http://www.sciencedirect.com/science/article/pii/S1350417725001798Grape pomaceProcyanidinsUltrasound-assisted extractionNatural deep eutectic solventsAntioxidantMacroporous resin
spellingShingle Changsen Wang
Yilin You
Weidong Huang
Jicheng Zhan
Efficient recovery of procyanidins from grape residue by UAE-NADES and macroporous resin
Ultrasonics Sonochemistry
Grape pomace
Procyanidins
Ultrasound-assisted extraction
Natural deep eutectic solvents
Antioxidant
Macroporous resin
title Efficient recovery of procyanidins from grape residue by UAE-NADES and macroporous resin
title_full Efficient recovery of procyanidins from grape residue by UAE-NADES and macroporous resin
title_fullStr Efficient recovery of procyanidins from grape residue by UAE-NADES and macroporous resin
title_full_unstemmed Efficient recovery of procyanidins from grape residue by UAE-NADES and macroporous resin
title_short Efficient recovery of procyanidins from grape residue by UAE-NADES and macroporous resin
title_sort efficient recovery of procyanidins from grape residue by uae nades and macroporous resin
topic Grape pomace
Procyanidins
Ultrasound-assisted extraction
Natural deep eutectic solvents
Antioxidant
Macroporous resin
url http://www.sciencedirect.com/science/article/pii/S1350417725001798
work_keys_str_mv AT changsenwang efficientrecoveryofprocyanidinsfromgraperesiduebyuaenadesandmacroporousresin
AT yilinyou efficientrecoveryofprocyanidinsfromgraperesiduebyuaenadesandmacroporousresin
AT weidonghuang efficientrecoveryofprocyanidinsfromgraperesiduebyuaenadesandmacroporousresin
AT jichengzhan efficientrecoveryofprocyanidinsfromgraperesiduebyuaenadesandmacroporousresin