Current status on M. pneumoniae: Clinical Features and Management Strategies
Background: The COVID-19 pandemic has significantly impacted Mycoplasma pneumoniae (MP), leading to a decline in prevalence and delayed resurgence. The rise of macrolide-resistant M. pneumoniae complicates treatment, necessitating alternative antibiotics. Aim: This review examines the impact of...
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| Format: | Article |
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Nigerian Medical Association, Akwa Ibom State Branch
2025-04-01
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| Series: | Ibom Medical Journal |
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| Online Access: | http://ibommedicaljournal.org/index.php/imjhome/article/view/684 |
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| author | Asit K Bragadeeshwaran N Janhavi MS Shamina S Lavanya SV Suria P Muthu PP |
| author_facet | Asit K Bragadeeshwaran N Janhavi MS Shamina S Lavanya SV Suria P Muthu PP |
| author_sort | Asit K |
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Background: The COVID-19 pandemic has significantly impacted Mycoplasma pneumoniae (MP), leading to a decline in prevalence and delayed resurgence. The rise of macrolide-resistant M. pneumoniae complicates treatment, necessitating alternative antibiotics.
Aim: This review examines the impact of COVID-19 on M. pneumoniae (MP) epidemiology, rising macrolide resistance, and evolving treatment challenges. It highlights advanced diagnostics, alternative antibiotics, and future research needs for predictive biomarkers and novel therapies. Continuous surveillance and adaptive strategies are crucial for optimizing MP infection management in a post-pandemic world.
Methods: A comprehensive review of recent literature was conducted, focusing on epidemiological trends, antimicrobial resistance patterns, diagnostic innovations, and treatment strategies for MP infections. Data were extracted from peer-reviewed journals, clinical studies, and global health reports to provide an updated perspective on the evolving landscape of MP infections.
Results: M. pneumoniae infections, which declined during COVID-19 due to non-pharmaceutical interventions, have resurged post-pandemic due to macrolide-resistant infections. Rapid molecular diagnostic tools and predictive biomarkers are needed to improve treatment outcomes and optimize infection management in pediatric patients.
Conclusion: Managing MP infections in a post-pandemic world requires continuous surveillance, advanced diagnostics, and adaptive treatment strategies. The increasing prevalence of MRMP underscores the need for alternative therapeutic options and robust antimicrobial stewardship. Future research should focus on predictive factors for treatment response, novel drug development, and the long-term impact of epidemiological shifts on respiratory infections.
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| format | Article |
| id | doaj-art-e80ed4d4a2ac41d8ac8d00f494c3b89d |
| institution | Kabale University |
| issn | 1597-7188 2735-9964 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nigerian Medical Association, Akwa Ibom State Branch |
| record_format | Article |
| series | Ibom Medical Journal |
| spelling | doaj-art-e80ed4d4a2ac41d8ac8d00f494c3b89d2025-08-20T03:25:22ZengNigerian Medical Association, Akwa Ibom State BranchIbom Medical Journal1597-71882735-99642025-04-0118210.61386/imj.v18i2.684Current status on M. pneumoniae: Clinical Features and Management StrategiesAsit K0Bragadeeshwaran N1Janhavi MS2Shamina S3Lavanya SV4Suria P5Muthu PP6Department of Environmental Science, Rajdhani College (University of Delhi), Raja Garden, New Delhi- 110015Department of Paediatrics, Velammal Medical College and research institute, Madurai-625009Department of Pathology, Sree Balaji Medical College and Hospital, ChennaiDepartment of Biochemistry, RVS College of Arts and Science, Sulur Coimbatore-641402ACS Medical college and hospital, Dr.M.G.R. Educational and Research Institute, Maduravoyal, ChennaiDepartment of Pharmaceutical Sciences Chettinad School of Pharmaceutical Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam – 603103, Tamil Nadu, IndiaDepartment of Pharmaceutical, Biotechnology, Surya college of Pharmacy, India Background: The COVID-19 pandemic has significantly impacted Mycoplasma pneumoniae (MP), leading to a decline in prevalence and delayed resurgence. The rise of macrolide-resistant M. pneumoniae complicates treatment, necessitating alternative antibiotics. Aim: This review examines the impact of COVID-19 on M. pneumoniae (MP) epidemiology, rising macrolide resistance, and evolving treatment challenges. It highlights advanced diagnostics, alternative antibiotics, and future research needs for predictive biomarkers and novel therapies. Continuous surveillance and adaptive strategies are crucial for optimizing MP infection management in a post-pandemic world. Methods: A comprehensive review of recent literature was conducted, focusing on epidemiological trends, antimicrobial resistance patterns, diagnostic innovations, and treatment strategies for MP infections. Data were extracted from peer-reviewed journals, clinical studies, and global health reports to provide an updated perspective on the evolving landscape of MP infections. Results: M. pneumoniae infections, which declined during COVID-19 due to non-pharmaceutical interventions, have resurged post-pandemic due to macrolide-resistant infections. Rapid molecular diagnostic tools and predictive biomarkers are needed to improve treatment outcomes and optimize infection management in pediatric patients. Conclusion: Managing MP infections in a post-pandemic world requires continuous surveillance, advanced diagnostics, and adaptive treatment strategies. The increasing prevalence of MRMP underscores the need for alternative therapeutic options and robust antimicrobial stewardship. Future research should focus on predictive factors for treatment response, novel drug development, and the long-term impact of epidemiological shifts on respiratory infections. http://ibommedicaljournal.org/index.php/imjhome/article/view/684Clinical featuresDiagnostic advancesM. pneumoniaManagement strategiestreatment protocols |
| spellingShingle | Asit K Bragadeeshwaran N Janhavi MS Shamina S Lavanya SV Suria P Muthu PP Current status on M. pneumoniae: Clinical Features and Management Strategies Ibom Medical Journal Clinical features Diagnostic advances M. pneumonia Management strategies treatment protocols |
| title | Current status on M. pneumoniae: Clinical Features and Management Strategies |
| title_full | Current status on M. pneumoniae: Clinical Features and Management Strategies |
| title_fullStr | Current status on M. pneumoniae: Clinical Features and Management Strategies |
| title_full_unstemmed | Current status on M. pneumoniae: Clinical Features and Management Strategies |
| title_short | Current status on M. pneumoniae: Clinical Features and Management Strategies |
| title_sort | current status on m pneumoniae clinical features and management strategies |
| topic | Clinical features Diagnostic advances M. pneumonia Management strategies treatment protocols |
| url | http://ibommedicaljournal.org/index.php/imjhome/article/view/684 |
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