Ribosome engineering of Myxococcus xanthus for enhancing the heterologous production of epothilones
Abstract Background Ribosome engineering is a semi-empirical technique used to select antibiotic-resistant mutants that exhibit altered secondary metabolism. This method has been demonstrated to effectively select mutants with enhanced synthesis of natural products in many bacterial species, includi...
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| Main Authors: | Xu Kang, Xiao-ran Yue, Chen-xi Wang, Jia-rui Wang, Jun-ning Zhao, Zhao-peng Yang, Qin-ke Fu, Chang-sheng Wu, Wei Hu, Yue-zhong Li, Xin-jing Yue |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-12-01
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| Series: | Microbial Cell Factories |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12934-024-02627-3 |
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