Moon craters in the brain: the striking lesions of Baló’s concentric sclerosis in a young adult
Abstract Background Baló’s concentric sclerosis (BCS) is a rare demyelinating disorder distinguished by its hallmark imaging feature of concentric layers of demyelination on magnetic resonance imaging (MRI). Despite its distinct radiological presentation, the pathogenesis and clinical significance o...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2025-08-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
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| Online Access: | https://doi.org/10.1186/s43055-025-01546-6 |
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| author | Ismail Mohamed Halfi Firdaous Touarsa Meriem Fikri Mohamed Jiddane |
| author_facet | Ismail Mohamed Halfi Firdaous Touarsa Meriem Fikri Mohamed Jiddane |
| author_sort | Ismail Mohamed Halfi |
| collection | DOAJ |
| description | Abstract Background Baló’s concentric sclerosis (BCS) is a rare demyelinating disorder distinguished by its hallmark imaging feature of concentric layers of demyelination on magnetic resonance imaging (MRI). Despite its distinct radiological presentation, the pathogenesis and clinical significance of BCS remain poorly understood, making the reporting of such cases crucial for advancing knowledge about its diagnosis and management. Through this case report, we aimed to highlight the clinical and radiological features of BCS and emphasise the role of MRI in its early diagnosis and management. Case presentation We present a case of BCS characterised by a severe clinical presentation and a striking radiological profile. The patient exhibited profound neurological deficits, and a brain MRI was performed, demonstrating the hallmark concentric demyelination pattern. Diagnosis was based on clinical presentation and characteristic imaging findings. High-dose corticosteroid therapy led to significant clinical recovery and marked radiological improvement. Conclusions This case contributes to a deeper understanding of the pathophysiological processes behind BCS and underscores the importance of recognising its characteristic imaging features. Improved awareness may enhance diagnostic accuracy and influence therapeutic approaches for this rare condition. |
| format | Article |
| id | doaj-art-e801d861f44947c8abbc06a6784bebdd |
| institution | Kabale University |
| issn | 2090-4762 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj-art-e801d861f44947c8abbc06a6784bebdd2025-08-20T03:47:10ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622025-08-015611510.1186/s43055-025-01546-6Moon craters in the brain: the striking lesions of Baló’s concentric sclerosis in a young adultIsmail Mohamed Halfi0Firdaous Touarsa1Meriem Fikri2Mohamed Jiddane3Hospital of Specialties, Mohammed V UniversityHospital of Specialties, Mohammed V UniversityHospital of Specialties, Mohammed V UniversityHospital of Specialties, Mohammed V UniversityAbstract Background Baló’s concentric sclerosis (BCS) is a rare demyelinating disorder distinguished by its hallmark imaging feature of concentric layers of demyelination on magnetic resonance imaging (MRI). Despite its distinct radiological presentation, the pathogenesis and clinical significance of BCS remain poorly understood, making the reporting of such cases crucial for advancing knowledge about its diagnosis and management. Through this case report, we aimed to highlight the clinical and radiological features of BCS and emphasise the role of MRI in its early diagnosis and management. Case presentation We present a case of BCS characterised by a severe clinical presentation and a striking radiological profile. The patient exhibited profound neurological deficits, and a brain MRI was performed, demonstrating the hallmark concentric demyelination pattern. Diagnosis was based on clinical presentation and characteristic imaging findings. High-dose corticosteroid therapy led to significant clinical recovery and marked radiological improvement. Conclusions This case contributes to a deeper understanding of the pathophysiological processes behind BCS and underscores the importance of recognising its characteristic imaging features. Improved awareness may enhance diagnostic accuracy and influence therapeutic approaches for this rare condition.https://doi.org/10.1186/s43055-025-01546-6Baló’s concentric sclerosisPathophysiologyMRIMultiple sclerosis |
| spellingShingle | Ismail Mohamed Halfi Firdaous Touarsa Meriem Fikri Mohamed Jiddane Moon craters in the brain: the striking lesions of Baló’s concentric sclerosis in a young adult The Egyptian Journal of Radiology and Nuclear Medicine Baló’s concentric sclerosis Pathophysiology MRI Multiple sclerosis |
| title | Moon craters in the brain: the striking lesions of Baló’s concentric sclerosis in a young adult |
| title_full | Moon craters in the brain: the striking lesions of Baló’s concentric sclerosis in a young adult |
| title_fullStr | Moon craters in the brain: the striking lesions of Baló’s concentric sclerosis in a young adult |
| title_full_unstemmed | Moon craters in the brain: the striking lesions of Baló’s concentric sclerosis in a young adult |
| title_short | Moon craters in the brain: the striking lesions of Baló’s concentric sclerosis in a young adult |
| title_sort | moon craters in the brain the striking lesions of balo s concentric sclerosis in a young adult |
| topic | Baló’s concentric sclerosis Pathophysiology MRI Multiple sclerosis |
| url | https://doi.org/10.1186/s43055-025-01546-6 |
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