Non-invasive intraductal oncocytic papillary neoplasm forming a protruding lesion toward the duodenum from the accessory papilla: a case report
Abstract Background Intraductal oncocytic papillary neoplasm (IOPN), previously classified as a subtype of intraductal papillary mucinous neoplasm (IPMN), has been described as an independent disease by the WHO since 2019. IOPN is a rare tumor, with few reported cases. Herein, we report a case of re...
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Japan Surgical Society
2024-02-01
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| Series: | Surgical Case Reports |
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| Online Access: | https://doi.org/10.1186/s40792-024-01841-w |
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| author | Shinnosuke Kawahara Naoto Yamamoto Kota Washimi Rei Kanemoto Daishi Takahashi Yuto Kamioka Itaru Hashimoto Mariko Kamiya Aya Kato Yukio Maezawa Keisuke Kazama Masaaki Murakawa Sho Sawazaki Toru Aoyama Hiroshi Tamagawa Takashi Oshima Norio Yukawa Yasushi Rino Tomoyuki Yokose Aya Saito Soichiro Morinaga |
| author_facet | Shinnosuke Kawahara Naoto Yamamoto Kota Washimi Rei Kanemoto Daishi Takahashi Yuto Kamioka Itaru Hashimoto Mariko Kamiya Aya Kato Yukio Maezawa Keisuke Kazama Masaaki Murakawa Sho Sawazaki Toru Aoyama Hiroshi Tamagawa Takashi Oshima Norio Yukawa Yasushi Rino Tomoyuki Yokose Aya Saito Soichiro Morinaga |
| author_sort | Shinnosuke Kawahara |
| collection | DOAJ |
| description | Abstract Background Intraductal oncocytic papillary neoplasm (IOPN), previously classified as a subtype of intraductal papillary mucinous neoplasm (IPMN), has been described as an independent disease by the WHO since 2019. IOPN is a rare tumor, with few reported cases. Herein, we report a case of resected non-invasive IOPN that formed a lesion protruding toward the duodenum from the accessory papilla. Case presentation An 80-year-old woman was referred to our hospital because of a giant mass in the pancreatic head detected on abdominal contrast-enhanced computed tomography (CT) performed for a close examination of a mass in the right breast. CT revealed a 90-mm-sized tumor with a mixture of solid and cystic components, with contrast enhancement in the pancreatic head, and a dilated main pancreatic duct. Esophagogastroduodenoscopy revealed a semi-circumferential papillary tumor protruding toward the duodenal lumen, which did not protrude from the papilla of Vater. Transpapillary biopsy led to a preoperative diagnosis of IPMN with an associated invasive carcinoma. As there were no distant metastasis, open subtotal stomach-preserving pancreaticoduodenectomy was performed. Analysis of the surgical specimen and histopathological examination revealed that the tumor was an IOPN that protruded toward the duodenal mucosa from the accessory papilla while replacing the duodenal mucosa with no obvious stromal invasion. Conclusion IOPN is a rare and poorly recognized tumor with few reported cases. There have been no reports describing IOPN forming a protruding lesion toward the duodenum from the accessory papilla. Therefore, further accumulation of cases such as this one is important to advance the study of IOPN. |
| format | Article |
| id | doaj-art-e7f5166449684c39a023b5d15c9f50ee |
| institution | Kabale University |
| issn | 2198-7793 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Japan Surgical Society |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj-art-e7f5166449684c39a023b5d15c9f50ee2025-08-20T03:39:11ZengJapan Surgical SocietySurgical Case Reports2198-77932024-02-011011810.1186/s40792-024-01841-wNon-invasive intraductal oncocytic papillary neoplasm forming a protruding lesion toward the duodenum from the accessory papilla: a case reportShinnosuke Kawahara0Naoto Yamamoto1Kota Washimi2Rei Kanemoto3Daishi Takahashi4Yuto Kamioka5Itaru Hashimoto6Mariko Kamiya7Aya Kato8Yukio Maezawa9Keisuke Kazama10Masaaki Murakawa11Sho Sawazaki12Toru Aoyama13Hiroshi Tamagawa14Takashi Oshima15Norio Yukawa16Yasushi Rino17Tomoyuki Yokose18Aya Saito19Soichiro Morinaga20Department of Gastrointestinal Surgery, Kanagawa Cancer CenterDepartment of Gastrointestinal Surgery, Kanagawa Cancer CenterDepartment of Pathology, Kanagawa Cancer CenterDepartment of Gastrointestinal Surgery, Kanagawa Cancer CenterDepartment of Gastrointestinal Surgery, Kanagawa Cancer CenterDepartment of Gastrointestinal Surgery, Kanagawa Cancer CenterDepartment of Surgery, Yokohama City UniversityDepartment of Gastrointestinal Surgery, Kanagawa Cancer CenterDepartment of Surgery, Yokohama City UniversityDepartment of Surgery, Yokohama City UniversityDepartment of Surgery, Yokohama City UniversityDepartment of Gastrointestinal Surgery, Kanagawa Cancer CenterDepartment of Surgery, Yokohama City UniversityDepartment of Surgery, Yokohama City UniversityDepartment of Surgery, Yokohama City UniversityDepartment of Gastrointestinal Surgery, Kanagawa Cancer CenterDepartment of Surgery, Yokohama City UniversityDepartment of Surgery, Yokohama City UniversityDepartment of Pathology, Kanagawa Cancer CenterDepartment of Surgery, Yokohama City UniversityDepartment of Gastrointestinal Surgery, Kanagawa Cancer CenterAbstract Background Intraductal oncocytic papillary neoplasm (IOPN), previously classified as a subtype of intraductal papillary mucinous neoplasm (IPMN), has been described as an independent disease by the WHO since 2019. IOPN is a rare tumor, with few reported cases. Herein, we report a case of resected non-invasive IOPN that formed a lesion protruding toward the duodenum from the accessory papilla. Case presentation An 80-year-old woman was referred to our hospital because of a giant mass in the pancreatic head detected on abdominal contrast-enhanced computed tomography (CT) performed for a close examination of a mass in the right breast. CT revealed a 90-mm-sized tumor with a mixture of solid and cystic components, with contrast enhancement in the pancreatic head, and a dilated main pancreatic duct. Esophagogastroduodenoscopy revealed a semi-circumferential papillary tumor protruding toward the duodenal lumen, which did not protrude from the papilla of Vater. Transpapillary biopsy led to a preoperative diagnosis of IPMN with an associated invasive carcinoma. As there were no distant metastasis, open subtotal stomach-preserving pancreaticoduodenectomy was performed. Analysis of the surgical specimen and histopathological examination revealed that the tumor was an IOPN that protruded toward the duodenal mucosa from the accessory papilla while replacing the duodenal mucosa with no obvious stromal invasion. Conclusion IOPN is a rare and poorly recognized tumor with few reported cases. There have been no reports describing IOPN forming a protruding lesion toward the duodenum from the accessory papilla. Therefore, further accumulation of cases such as this one is important to advance the study of IOPN.https://doi.org/10.1186/s40792-024-01841-wIntraductal oncocytic papillary neoplasmPancreasAccessory papillaNon-invasive |
| spellingShingle | Shinnosuke Kawahara Naoto Yamamoto Kota Washimi Rei Kanemoto Daishi Takahashi Yuto Kamioka Itaru Hashimoto Mariko Kamiya Aya Kato Yukio Maezawa Keisuke Kazama Masaaki Murakawa Sho Sawazaki Toru Aoyama Hiroshi Tamagawa Takashi Oshima Norio Yukawa Yasushi Rino Tomoyuki Yokose Aya Saito Soichiro Morinaga Non-invasive intraductal oncocytic papillary neoplasm forming a protruding lesion toward the duodenum from the accessory papilla: a case report Surgical Case Reports Intraductal oncocytic papillary neoplasm Pancreas Accessory papilla Non-invasive |
| title | Non-invasive intraductal oncocytic papillary neoplasm forming a protruding lesion toward the duodenum from the accessory papilla: a case report |
| title_full | Non-invasive intraductal oncocytic papillary neoplasm forming a protruding lesion toward the duodenum from the accessory papilla: a case report |
| title_fullStr | Non-invasive intraductal oncocytic papillary neoplasm forming a protruding lesion toward the duodenum from the accessory papilla: a case report |
| title_full_unstemmed | Non-invasive intraductal oncocytic papillary neoplasm forming a protruding lesion toward the duodenum from the accessory papilla: a case report |
| title_short | Non-invasive intraductal oncocytic papillary neoplasm forming a protruding lesion toward the duodenum from the accessory papilla: a case report |
| title_sort | non invasive intraductal oncocytic papillary neoplasm forming a protruding lesion toward the duodenum from the accessory papilla a case report |
| topic | Intraductal oncocytic papillary neoplasm Pancreas Accessory papilla Non-invasive |
| url | https://doi.org/10.1186/s40792-024-01841-w |
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